Amlodipine Drug Interactions

208Total Interactions
3Severe
55Moderate
1Mild
DrugSeveritySummary
Magnesium SEVERE intravenous Magnesium potentially increases the risk of hypotension when given with Amlodipine in...
Mefloquine SEVERE Mefloquine is predicted to increase the risk of bradycardia when given with Amlodipine. Manufactu...
Nirmatrelvir SEVERE Nirmatrelvir boosted with ritonavir is predicted to increase the concentration of Amlodipine. Man...
Apalutamide MODERATE Apalutamide is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and...
Aprepitant MODERATE Aprepitant is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and ...
Atazanavir MODERATE Atazanavir is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and ...
Berotralstat MODERATE Berotralstat is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor an...
Bosentan MODERATE Bosentan is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and ad...
Carbamazepine MODERATE Carbamazepine is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor a...
Cenobamate MODERATE Cenobamate is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and ...
Ceritinib MODERATE Ceritinib is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and a...
Clarithromycin MODERATE Clarithromycin is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor ...
Cobicistat MODERATE Cobicistat is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and ...
Crizotinib MODERATE Crizotinib is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and ...
Dabrafenib MODERATE Dabrafenib is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and ...
Darunavir MODERATE Darunavir is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and a...
Diltiazem MODERATE Diltiazem is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and a...
Dronedarone MODERATE Dronedarone is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and...
Efavirenz MODERATE Efavirenz is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and a...
Encorafenib MODERATE Encorafenib is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and...
Enzalutamide MODERATE Enzalutamide is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor an...
Erythromycin MODERATE Erythromycin is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor an...
Etravirine MODERATE Etravirine is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and ...
Fedratinib MODERATE Fedratinib is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and ...
Fluconazole MODERATE Fluconazole is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and...
Fosamprenavir MODERATE Fosamprenavir is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor a...
Fosphenytoin MODERATE Fosphenytoin is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor an...
Grazoprevir MODERATE Grazoprevir is predicted to increase the concentration of Amlodipine. Manufacturer makes no recom...
Idelalisib MODERATE Idelalisib is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and ...
Imatinib MODERATE Imatinib is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and ad...
Isavuconazole MODERATE Isavuconazole is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor a...
Itraconazole MODERATE Itraconazole is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor an...
Ivosidenib MODERATE Ivosidenib is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and ...
Ketoconazole MODERATE Ketoconazole is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor an...
Letermovir MODERATE Letermovir is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and ...
Lomitapide MODERATE Amlodipine is predicted to increase the exposure to Lomitapide. Manufacturer advises separate adm...
Lopinavir MODERATE Lopinavir is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and a...
Lorlatinib MODERATE Lorlatinib is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and ...
Lumacaftor MODERATE Lumacaftor is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and ...
Miconazole MODERATE Miconazole is predicted to increase the exposure to Amlodipine. Manufacturer advises use with cau...
Mitotane MODERATE Mitotane is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and ad...
Netupitant MODERATE Netupitant is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and ...
Nevirapine MODERATE Nevirapine is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and ...
Nilotinib MODERATE Nilotinib is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and a...
Phenobarbital MODERATE Phenobarbital is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor a...
Phenytoin MODERATE Phenytoin is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and a...
Posaconazole MODERATE Posaconazole is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor an...
Primidone MODERATE Primidone is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and a...
Rifampicin MODERATE Rifampicin is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and ...
Ritonavir MODERATE Ritonavir is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and a...
Simvastatin MODERATE Amlodipine causes a small increase in the exposure to Simvastatin. Manufacturer advises adjust Si...
Sotorasib MODERATE Sotorasib is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and a...
St John's wort MODERATE St John's wort is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor ...
Temsirolimus MODERATE Temsirolimus is predicted to increase the risk of angioedema when given with Amlodipine. Manufact...
Tocilizumab MODERATE Tocilizumab is predicted to decrease the exposure to Amlodipine. Manufacturer advises monitor and...
Tucatinib MODERATE Tucatinib is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and a...
Verapamil MODERATE Verapamil is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and a...
Voriconazole MODERATE Voriconazole is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor an...
Grapefruit MILD Grapefruit juice very slightly increases the exposure to Amlodipine. Manufacturer advises avoid.
Acebutolol LOW Both Amlodipine and Acebutolol can increase the risk of hypotension.
Alcohol LOW Both Amlodipine and Alcohol can increase the risk of hypotension.
Alfuzosin LOW Both Amlodipine and Alfuzosin can increase the risk of hypotension.
Aliskiren LOW Both Amlodipine and Aliskiren can increase the risk of hypotension.
Alprostadil LOW Both Amlodipine and Alprostadil can increase the risk of hypotension.
Amantadine LOW Both Amlodipine and Amantadine can increase the risk of hypotension.
Amitriptyline LOW Both Amlodipine and Amitriptyline can increase the risk of hypotension.
Apomorphine LOW Both Amlodipine and Apomorphine can increase the risk of hypotension.
Apraclonidine LOW Both Amlodipine and Apraclonidine can increase the risk of hypotension.
Aripiprazole LOW Both Amlodipine and Aripiprazole can increase the risk of hypotension.
Asenapine LOW Both Amlodipine and Asenapine can increase the risk of hypotension.
Atenolol LOW Both Amlodipine and Atenolol can increase the risk of hypotension.
Avanafil LOW Both Amlodipine and Avanafil can increase the risk of hypotension.
Azilsartan LOW Both Amlodipine and Azilsartan can increase the risk of hypotension.
Baclofen LOW Both Amlodipine and Baclofen can increase the risk of hypotension.
Bendroflumethiazide LOW Both Amlodipine and Bendroflumethiazide can increase the risk of hypotension.
Benperidol LOW Both Amlodipine and Benperidol can increase the risk of hypotension.
Betaxolol LOW Both Amlodipine and Betaxolol can increase the risk of hypotension.
Bisoprolol LOW Both Amlodipine and Bisoprolol can increase the risk of hypotension.
Bortezomib LOW Both Amlodipine and Bortezomib can increase the risk of hypotension.
Brimonidine LOW Both Amlodipine and Brimonidine can increase the risk of hypotension.
Bromocriptine LOW Both Amlodipine and Bromocriptine can increase the risk of hypotension.
Bumetanide LOW Both Amlodipine and Bumetanide can increase the risk of hypotension.
Cabergoline LOW Both Amlodipine and Cabergoline can increase the risk of hypotension.
Canagliflozin LOW Both Amlodipine and Canagliflozin can increase the risk of hypotension.
Candesartan LOW Both Amlodipine and Candesartan can increase the risk of hypotension.
Captopril LOW Both Amlodipine and Captopril can increase the risk of hypotension.
Cariprazine LOW Both Amlodipine and Cariprazine can increase the risk of hypotension.
Carvedilol LOW Both Amlodipine and Carvedilol can increase the risk of hypotension.
Celiprolol LOW Both Amlodipine and Celiprolol can increase the risk of hypotension.
Chlorothiazide LOW Both Amlodipine and Chlorothiazide can increase the risk of hypotension.
Chlorpromazine LOW Both Amlodipine and Chlorpromazine can increase the risk of hypotension.
Chlortalidone LOW Both Amlodipine and Chlortalidone can increase the risk of hypotension.
Clomipramine LOW Both Amlodipine and Clomipramine can increase the risk of hypotension.
Clonidine LOW Both Amlodipine and Clonidine can increase the risk of hypotension.
Clozapine LOW Both Amlodipine and Clozapine can increase the risk of hypotension.
Dapagliflozin LOW Both Amlodipine and Dapagliflozin can increase the risk of hypotension.
Desflurane LOW Both Amlodipine and Desflurane can increase the risk of hypotension.
Diazoxide LOW Both Amlodipine and Diazoxide can increase the risk of hypotension.
Dipyridamole LOW Both Amlodipine and Dipyridamole can increase the risk of hypotension.
Dosulepin LOW Both Amlodipine and Dosulepin can increase the risk of hypotension.
Doxazosin LOW Both Amlodipine and Doxazosin can increase the risk of hypotension.
Doxepin LOW Both Amlodipine and Doxepin can increase the risk of hypotension.
Droperidol LOW Both Amlodipine and Droperidol can increase the risk of hypotension.
Empagliflozin LOW Both Amlodipine and Empagliflozin can increase the risk of hypotension.
Enalapril LOW Both Amlodipine and Enalapril can increase the risk of hypotension.
Eplerenone LOW Both Amlodipine and Eplerenone can increase the risk of hypotension.
Epoprostenol LOW Both Amlodipine and Epoprostenol can increase the risk of hypotension.
Eprosartan LOW Both Amlodipine and Eprosartan can increase the risk of hypotension.
Ertugliflozin LOW Both Amlodipine and Ertugliflozin can increase the risk of hypotension.
Esketamine LOW Both Amlodipine and Esketamine can increase the risk of hypotension.
Esmolol LOW Both Amlodipine and Esmolol can increase the risk of hypotension.
Etomidate LOW Both Amlodipine and Etomidate can increase the risk of hypotension.
Finerenone LOW Both Amlodipine and Finerenone can increase the risk of hypotension.
Flupentixol LOW Both Amlodipine and Flupentixol can increase the risk of hypotension.
Fosinopril LOW Both Amlodipine and Fosinopril can increase the risk of hypotension.
Foslevodopa LOW Both Amlodipine and Foslevodopa can increase the risk of hypotension.
Furosemide LOW Both Amlodipine and Furosemide can increase the risk of hypotension.
Glyceryl trinitrate LOW Both Amlodipine and Glyceryl trinitrate can increase the risk of hypotension.
Guanfacine LOW Both Amlodipine and Guanfacine can increase the risk of hypotension.
Haloperidol LOW Both Amlodipine and Haloperidol can increase the risk of hypotension.
Hydralazine LOW Both Amlodipine and Hydralazine can increase the risk of hypotension.
Hydrochlorothiazide LOW Both Amlodipine and Hydrochlorothiazide can increase the risk of hypotension.
Hydroflumethiazide LOW Both Amlodipine and Hydroflumethiazide can increase the risk of hypotension.
Iloprost LOW Both Amlodipine and Iloprost can increase the risk of hypotension.
Imidapril LOW Both Amlodipine and Imidapril can increase the risk of hypotension.
Imipramine LOW Both Amlodipine and Imipramine can increase the risk of hypotension.
Indapamide LOW Both Amlodipine and Indapamide can increase the risk of hypotension.
Indoramin LOW Both Amlodipine and Indoramin can increase the risk of hypotension.
Irbesartan LOW Both Amlodipine and Irbesartan can increase the risk of hypotension.
Isocarboxazid LOW Both Amlodipine and Isocarboxazid can increase the risk of hypotension.
Isoflurane LOW Both Amlodipine and Isoflurane can increase the risk of hypotension.
Isosorbide dinitrate LOW Both Amlodipine and Isosorbide dinitrate can increase the risk of hypotension.
Isosorbide mononitrate LOW Both Amlodipine and Isosorbide mononitrate can increase the risk of hypotension.
Ketamine LOW Both Amlodipine and Ketamine can increase the risk of hypotension.
Labetalol LOW Both Amlodipine and Labetalol can increase the risk of hypotension.
Landiolol LOW Both Amlodipine and Landiolol can increase the risk of hypotension.
Levobunolol LOW Both Amlodipine and Levobunolol can increase the risk of hypotension.
Levodopa LOW Both Amlodipine and Levodopa can increase the risk of hypotension.
Levomepromazine LOW Both Amlodipine and Levomepromazine can increase the risk of hypotension.
Lisinopril LOW Both Amlodipine and Lisinopril can increase the risk of hypotension.
Lofepramine LOW Both Amlodipine and Lofepramine can increase the risk of hypotension.
Lofexidine LOW Both Amlodipine and Lofexidine can increase the risk of hypotension.
Losartan LOW Both Amlodipine and Losartan can increase the risk of hypotension.
Loxapine LOW Both Amlodipine and Loxapine can increase the risk of hypotension.
Lurasidone LOW Both Amlodipine and Lurasidone can increase the risk of hypotension.
Methoxyflurane LOW Both Amlodipine and Methoxyflurane can increase the risk of hypotension.
Methyldopa LOW Both Amlodipine and Methyldopa can increase the risk of hypotension.
Metolazone LOW Both Amlodipine and Metolazone can increase the risk of hypotension.
Metoprolol LOW Both Amlodipine and Metoprolol can increase the risk of hypotension.
Minoxidil LOW Both Amlodipine and Minoxidil can increase the risk of hypotension.
Moxonidine LOW Both Amlodipine and Moxonidine can increase the risk of hypotension.
Nadolol LOW Both Amlodipine and Nadolol can increase the risk of hypotension.
Nebivolol LOW Both Amlodipine and Nebivolol can increase the risk of hypotension.
Nicorandil LOW Both Amlodipine and Nicorandil can increase the risk of hypotension.
Nitroprusside LOW Both Amlodipine and Nitroprusside can increase the risk of hypotension.
Nitrous oxide LOW Both Amlodipine and Nitrous oxide can increase the risk of hypotension.
Nortriptyline LOW Both Amlodipine and Nortriptyline can increase the risk of hypotension.
Olanzapine LOW Both Amlodipine and Olanzapine can increase the risk of hypotension.
Olmesartan LOW Both Amlodipine and Olmesartan can increase the risk of hypotension.
Paliperidone LOW Both Amlodipine and Paliperidone can increase the risk of hypotension.
Pericyazine LOW Both Amlodipine and Pericyazine can increase the risk of hypotension.
Perindopril LOW Both Amlodipine and Perindopril can increase the risk of hypotension.
Phenelzine LOW Both Amlodipine and Phenelzine can increase the risk of hypotension.
Pimozide LOW Both Amlodipine and Pimozide can increase the risk of hypotension.
Pindolol LOW Both Amlodipine and Pindolol can increase the risk of hypotension.
Pramipexole LOW Both Amlodipine and Pramipexole can increase the risk of hypotension.
Prazosin LOW Both Amlodipine and Prazosin can increase the risk of hypotension.
Prochlorperazine LOW Both Amlodipine and Prochlorperazine can increase the risk of hypotension.
Promazine LOW Both Amlodipine and Promazine can increase the risk of hypotension.
Propofol LOW Both Amlodipine and Propofol can increase the risk of hypotension.
Propranolol LOW Both Amlodipine and Propranolol can increase the risk of hypotension.
Quetiapine LOW Both Amlodipine and Quetiapine can increase the risk of hypotension.
Quinagolide LOW Both Amlodipine and Quinagolide can increase the risk of hypotension.
Quinapril LOW Both Amlodipine and Quinapril can increase the risk of hypotension.
Ramipril LOW Both Amlodipine and Ramipril can increase the risk of hypotension.
Riociguat LOW Both Amlodipine and Riociguat can increase the risk of hypotension.
Risperidone LOW Both Amlodipine and Risperidone can increase the risk of hypotension.
Ropinirole LOW Both Amlodipine and Ropinirole can increase the risk of hypotension.
Rotigotine LOW Both Amlodipine and Rotigotine can increase the risk of hypotension.
Sacubitril LOW Both Amlodipine and Sacubitril can increase the risk of hypotension.
Sapropterin LOW Both Amlodipine and Sapropterin can increase the risk of hypotension.
Selegiline LOW Both Amlodipine and Selegiline can increase the risk of hypotension.
Sevoflurane LOW Both Amlodipine and Sevoflurane can increase the risk of hypotension.
Sildenafil LOW Both Amlodipine and Sildenafil can increase the risk of hypotension.
Sodium oxybate LOW Both Amlodipine and Sodium oxybate can increase the risk of hypotension.
Sotalol LOW Both Amlodipine and Sotalol can increase the risk of hypotension.
Sparsentan LOW Both Amlodipine and Sparsentan can increase the risk of hypotension.
Spironolactone LOW Both Amlodipine and Spironolactone can increase the risk of hypotension.
Sulpiride LOW Both Amlodipine and Sulpiride can increase the risk of hypotension.
Tadalafil LOW Both Amlodipine and Tadalafil can increase the risk of hypotension.
Tamsulosin LOW Both Amlodipine and Tamsulosin can increase the risk of hypotension.
Telmisartan LOW Both Amlodipine and Telmisartan can increase the risk of hypotension.
Terazosin LOW Both Amlodipine and Terazosin can increase the risk of hypotension.
Thiopental LOW Both Amlodipine and Thiopental can increase the risk of hypotension.
Timolol LOW Both Amlodipine and Timolol can increase the risk of hypotension.
Tizanidine LOW Both Amlodipine and Tizanidine can increase the risk of hypotension.
Torasemide LOW Both Amlodipine and Torasemide can increase the risk of hypotension.
Trandolapril LOW Both Amlodipine and Trandolapril can increase the risk of hypotension.
Tranylcypromine LOW Both Amlodipine and Tranylcypromine can increase the risk of hypotension.
Treprostinil LOW Both Amlodipine and Treprostinil can increase the risk of hypotension.
Trifluoperazine LOW Both Amlodipine and Trifluoperazine can increase the risk of hypotension.
Trimipramine LOW Both Amlodipine and Trimipramine can increase the risk of hypotension.
Valsartan LOW Both Amlodipine and Valsartan can increase the risk of hypotension.
Vardenafil LOW Both Amlodipine and Vardenafil can increase the risk of hypotension.
Vericiguat LOW Both Amlodipine and Vericiguat can increase the risk of hypotension.
Vernakalant LOW Both Amlodipine and Vernakalant can increase the risk of hypotension.
Xipamide LOW Both Amlodipine and Xipamide can increase the risk of hypotension.
Zuclopenthixol LOW Both Amlodipine and Zuclopenthixol can increase the risk of hypotension.

Check Amlodipine against your patient's full medication list

InteractRx checks all drug combinations at once — built for GP surgery pharmacists.

Use the Free Checker