Aspirin Drug Interactions
207Total Interactions
120Severe
43Moderate
0Mild
| Drug | Severity | Summary |
|---|---|---|
| Acalabrutinib | SEVERE | Both Aspirin and Acalabrutinib can increase the risk of bleeding. |
| Aceclofenac | SEVERE | Both Aspirin and Aceclofenac can increase the risk of bleeding. |
| Acenocoumarol | SEVERE | Acenocoumarol causes bleeding, as can Aspirin ; concurrent use might increase the risk of develop... |
| Acetazolamide | SEVERE | Acetazolamide increases the risk of severe toxic reaction when given with Aspirin (high-dose). Ma... |
| Alprostadil | SEVERE | Both Aspirin and Alprostadil can increase the risk of bleeding. |
| Alteplase | SEVERE | Alteplase causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing ... |
| Anagrelide | SEVERE | Both Aspirin and Anagrelide can increase the risk of bleeding. |
| Apixaban | SEVERE | Apixaban causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing t... |
| Argatroban | SEVERE | Argatroban causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing... |
| Asparaginase | SEVERE | Asparaginase causes bleeding, as can Aspirin ; concurrent use might increase the risk of developi... |
| Avapritinib | SEVERE | Aspirin might increase the risk of bleeding when given with Avapritinib. Manufacturer advises mon... |
| Axitinib | SEVERE | Both Aspirin and Axitinib can increase the risk of bleeding. |
| Bemiparin | SEVERE | Bemiparin causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing ... |
| Bendroflumethiazide | SEVERE | Aspirin (high-dose) increases the risk of acute renal failure when given with Bendroflumethiazide... |
| Benzydamine | SEVERE | Both Aspirin and Benzydamine can increase the risk of bleeding. |
| Bevacizumab | SEVERE | Aspirin causes bleeding, as can Bevacizumab ; concurrent use might increase the risk of developin... |
| Bivalirudin | SEVERE | Bivalirudin causes bleeding, as can Aspirin ; concurrent use might increase the risk of developin... |
| Bosutinib | SEVERE | Both Aspirin and Bosutinib can increase the risk of bleeding. |
| Bromfenac | SEVERE | Both Aspirin and Bromfenac can increase the risk of bleeding. |
| Cabozantinib | SEVERE | Aspirin causes bleeding, as can Cabozantinib ; concurrent use might increase the risk of developi... |
| Cangrelor | SEVERE | Both Aspirin and Cangrelor can increase the risk of bleeding. |
| Caplacizumab | SEVERE | Aspirin causes bleeding, as can Caplacizumab ; concurrent use might increase the risk of developi... |
| Celecoxib | SEVERE | Both Aspirin and Celecoxib can increase the risk of bleeding. |
| Chlorothiazide | SEVERE | Aspirin (high-dose) increases the risk of acute renal failure when given with Chlorothiazide. Man... |
| Chlortalidone | SEVERE | Aspirin (high-dose) increases the risk of acute renal failure when given with Chlortalidone. Manu... |
| Cilostazol | SEVERE | Both Aspirin and Cilostazol can increase the risk of bleeding. |
| Citalopram | SEVERE | Both Aspirin and Citalopram can increase the risk of bleeding. |
| Clodronate | SEVERE | Aspirin (high-dose) is predicted to increase the risk of renal impairment when given with Clodron... |
| Clopidogrel | SEVERE | Both Aspirin and Clopidogrel can increase the risk of bleeding. |
| Cobimetinib | SEVERE | Aspirin causes bleeding, as can Cobimetinib ; concurrent use might increase the risk of developin... |
| Crisantaspase | SEVERE | Crisantaspase causes bleeding, as can Aspirin ; concurrent use might increase the risk of develop... |
| Dabigatran | SEVERE | Dabigatran causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing... |
| Dalteparin | SEVERE | Dalteparin causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing... |
| Danaparoid | SEVERE | Danaparoid causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing... |
| Dapoxetine | SEVERE | Both Aspirin and Dapoxetine can increase the risk of bleeding. |
| Dasatinib | SEVERE | Both Aspirin and Dasatinib can increase the risk of bleeding. |
| Deferasirox | SEVERE | Aspirin (high-dose) is predicted to increase the risk of gastrointestinal bleeds when given with ... |
| Dexketoprofen | SEVERE | Both Aspirin and Dexketoprofen can increase the risk of bleeding. |
| Diclofenac | SEVERE | Both Aspirin and Diclofenac can increase the risk of bleeding. |
| Dipyridamole | SEVERE | Both Aspirin and Dipyridamole can increase the risk of bleeding. |
| Donanemab | SEVERE | Donanemab can increase the risk of bleeding when given with Aspirin. Manufacturer makes no recomm... |
| Duloxetine | SEVERE | Both Aspirin and Duloxetine can increase the risk of bleeding. |
| Edoxaban | SEVERE | Edoxaban causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing t... |
| Enoxaparin | SEVERE | Enoxaparin causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing... |
| Epoprostenol | SEVERE | Both Aspirin and Epoprostenol can increase the risk of bleeding. |
| Eptifibatide | SEVERE | Eptifibatide causes bleeding, as can Aspirin ; concurrent use might increase the risk of developi... |
| Erlotinib | SEVERE | Erlotinib is predicted to increase the risk of gastrointestinal perforation when given with Aspir... |
| Escitalopram | SEVERE | Both Aspirin and Escitalopram can increase the risk of bleeding. |
| Etodolac | SEVERE | Both Aspirin and Etodolac can increase the risk of bleeding. |
| Etoricoxib | SEVERE | Both Aspirin and Etoricoxib can increase the risk of bleeding. |
| Fluoxetine | SEVERE | Both Aspirin and Fluoxetine can increase the risk of bleeding. |
| Flurbiprofen | SEVERE | Both Aspirin and Flurbiprofen can increase the risk of bleeding. |
| Fluvoxamine | SEVERE | Both Aspirin and Fluvoxamine can increase the risk of bleeding. |
| Fondaparinux | SEVERE | Fondaparinux causes bleeding, as can Aspirin ; concurrent use might increase the risk of developi... |
| Heparin | SEVERE | Heparin causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing th... |
| Hydrochlorothiazide | SEVERE | Aspirin (high-dose) increases the risk of acute renal failure when given with Hydrochlorothiazide... |
| Hydroflumethiazide | SEVERE | Aspirin (high-dose) increases the risk of acute renal failure when given with Hydroflumethiazide.... |
| Ibrutinib | SEVERE | Both Aspirin and Ibrutinib can increase the risk of bleeding. |
| Ibuprofen | SEVERE | Both Aspirin and Ibuprofen can increase the risk of bleeding. |
| Icosapent | SEVERE | Both Aspirin and Icosapent can increase the risk of bleeding. |
| Iloprost | SEVERE | Both Aspirin and Iloprost can increase the risk of bleeding. |
| Imatinib | SEVERE | Both Aspirin and Imatinib can increase the risk of bleeding. |
| Indapamide | SEVERE | Aspirin (high-dose) increases the risk of acute renal failure when given with Indapamide. Manufac... |
| Indometacin | SEVERE | Both Aspirin and Indometacin can increase the risk of bleeding. |
| Influenza vaccine (live) | SEVERE | Influenza vaccine (live) might increase the risk of Reye's syndrome when given with Aspirin. Manu... |
| Inotersen | SEVERE | Aspirin causes bleeding, as can Inotersen ; concurrent use might increase the risk of developing ... |
| Ketoprofen | SEVERE | Both Aspirin and Ketoprofen can increase the risk of bleeding. |
| Ketorolac | SEVERE | Both Aspirin and Ketorolac can increase the risk of bleeding. |
| Lecanemab | SEVERE | Lecanemab can increase the risk of bleeding when given with Aspirin. Manufacturer makes no recomm... |
| Lenvatinib | SEVERE | Both Aspirin and Lenvatinib can increase the risk of bleeding. |
| Mefenamic acid | SEVERE | Both Aspirin and Mefenamic acid can increase the risk of bleeding. |
| Meloxicam | SEVERE | Both Aspirin and Meloxicam can increase the risk of bleeding. |
| Methotrexate | SEVERE | Aspirin (high-dose) is predicted to increase the risk of toxicity when given with Methotrexate. M... |
| Metolazone | SEVERE | Aspirin (high-dose) increases the risk of acute renal failure when given with Metolazone. Manufac... |
| Nabumetone | SEVERE | Both Aspirin and Nabumetone can increase the risk of bleeding. |
| Naproxen | SEVERE | Both Aspirin and Naproxen can increase the risk of bleeding. |
| Nicorandil | SEVERE | Aspirin is predicted to increase the risk of gastrointestinal perforation when given with Nicoran... |
| Nicotinic acid | SEVERE | Nicotinic acid causes bleeding, as can Aspirin ; concurrent use might increase the risk of develo... |
| Nintedanib | SEVERE | Both Aspirin and Nintedanib can increase the risk of bleeding. |
| Omega-3-acid ethyl esters | SEVERE | Both Aspirin and Omega-3-acid ethyl esters can increase the risk of bleeding. |
| Parecoxib | SEVERE | Both Aspirin and Parecoxib can increase the risk of bleeding. |
| Paroxetine | SEVERE | Both Aspirin and Paroxetine can increase the risk of bleeding. |
| Pazopanib | SEVERE | Both Aspirin and Pazopanib can increase the risk of bleeding. |
| Pegaspargase | SEVERE | Pegaspargase causes bleeding, as can Aspirin ; concurrent use might increase the risk of developi... |
| Pemetrexed | SEVERE | Aspirin (high-dose) potentially increases the exposure to Pemetrexed. Manufacturer advises use wi... |
| Pentosan | SEVERE | Pentosan causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing t... |
| Phenazone | SEVERE | Both Aspirin and Phenazone can increase the risk of bleeding. |
| Phenindione | SEVERE | Phenindione causes bleeding, as can Aspirin ; concurrent use might increase the risk of developin... |
| Piroxicam | SEVERE | Both Aspirin and Piroxicam can increase the risk of bleeding. |
| Ponatinib | SEVERE | Both Aspirin and Ponatinib can increase the risk of bleeding. |
| Prasugrel | SEVERE | Both Aspirin and Prasugrel can increase the risk of bleeding. |
| Ranibizumab | SEVERE | Aspirin causes bleeding, as can Ranibizumab ; concurrent use might increase the risk of developin... |
| Regorafenib | SEVERE | Both Aspirin and Regorafenib can increase the risk of bleeding. |
| Rivaroxaban | SEVERE | Rivaroxaban causes bleeding, as can Aspirin ; concurrent use might increase the risk of developin... |
| Ruxolitinib | SEVERE | Aspirin causes bleeding, as can Ruxolitinib ; concurrent use might increase the risk of developin... |
| Selumetinib | SEVERE | Selumetinib might increase the risk of bleeding when given with Aspirin. Manufacturer advises mon... |
| Sertraline | SEVERE | Both Aspirin and Sertraline can increase the risk of bleeding. |
| Sorafenib | SEVERE | Both Aspirin and Sorafenib can increase the risk of bleeding. |
| Streptokinase | SEVERE | Streptokinase causes bleeding, as can Aspirin ; concurrent use might increase the risk of develop... |
| Sulindac | SEVERE | Both Aspirin and Sulindac can increase the risk of bleeding. |
| Sunitinib | SEVERE | Both Aspirin and Sunitinib can increase the risk of bleeding. |
| Tenecteplase | SEVERE | Tenecteplase causes bleeding, as can Aspirin ; concurrent use might increase the risk of developi... |
| Tenoxicam | SEVERE | Both Aspirin and Tenoxicam can increase the risk of bleeding. |
| Tiaprofenic acid | SEVERE | Both Aspirin and Tiaprofenic acid can increase the risk of bleeding. |
| Ticagrelor | SEVERE | Both Aspirin and Ticagrelor can increase the risk of bleeding. |
| Tinzaparin | SEVERE | Tinzaparin causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing... |
| Tirofiban | SEVERE | Tirofiban causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing ... |
| Tolfenamic acid | SEVERE | Both Aspirin and Tolfenamic acid can increase the risk of bleeding. |
| Trametinib | SEVERE | Aspirin causes bleeding, as can Trametinib ; concurrent use might increase the risk of developing... |
| Trastuzumab emtansine | SEVERE | Aspirin causes bleeding, as can Trastuzumab emtansine ; concurrent use might increase the risk of... |
| Treprostinil | SEVERE | Both Aspirin and Treprostinil can increase the risk of bleeding. |
| Urokinase | SEVERE | Urokinase causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing ... |
| Varicella-zoster vaccine | SEVERE | Varicella-zoster vaccine might increase the risk of Reye's syndrome when given with Aspirin. Manu... |
| Venlafaxine | SEVERE | Both Aspirin and Venlafaxine can increase the risk of bleeding. |
| Volanesorsen | SEVERE | Aspirin causes bleeding, as can Volanesorsen ; concurrent use might increase the risk of developi... |
| Vortioxetine | SEVERE | Both Aspirin and Vortioxetine can increase the risk of bleeding. |
| Warfarin | SEVERE | Warfarin causes bleeding, as can Aspirin ; concurrent use might increase the risk of developing t... |
| Xipamide | SEVERE | Aspirin (high-dose) increases the risk of acute renal failure when given with Xipamide. Manufactu... |
| Zanubrutinib | SEVERE | Both Aspirin and Zanubrutinib can increase the risk of bleeding. |
| Zidovudine | SEVERE | Zidovudine increases the risk of haematological toxicity when given with Aspirin (high-dose). Man... |
| Alendronate | MODERATE | Aspirin (high-dose) is predicted to increase the risk of gastrointestinal irritation when given w... |
| Amikacin | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Amikacin ; concurrent use might increase the ... |
| Amphotericin B | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Amphotericin B ; concurrent use might increas... |
| Antacids | MODERATE | oral Antacids decrease the absorption of oral Aspirin (high-dose). Manufacturer makes no recommen... |
| Beclometasone | MODERATE | Beclometasone is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (high... |
| Betamethasone | MODERATE | Betamethasone is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (high... |
| Bismuth | MODERATE | Bismuth subsalicylate is predicted to increase the risk of adverse effects when given with Aspiri... |
| Budesonide | MODERATE | Budesonide is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (high-do... |
| Bumetanide | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Bumetanide ; concurrent use might increase th... |
| Carboplatin | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Carboplatin ; concurrent use might increase t... |
| Chloroquine | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Chloroquine ; concurrent use might increase t... |
| Ciclesonide | MODERATE | Ciclesonide is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (high-d... |
| Cisplatin | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Cisplatin ; concurrent use might increase the... |
| Colistimethate | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Colistimethate ; concurrent use might increas... |
| Daptomycin | MODERATE | Aspirin (high-dose) increases the risk of renal impairment when given with Daptomycin. Manufactur... |
| Deflazacort | MODERATE | Deflazacort is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (high-d... |
| Dexamethasone | MODERATE | Dexamethasone is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (high... |
| Fludrocortisone | MODERATE | Fludrocortisone is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (hi... |
| Fluticasone | MODERATE | Fluticasone is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (high-d... |
| Furosemide | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Furosemide ; concurrent use might increase th... |
| Gentamicin | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Gentamicin ; concurrent use might increase th... |
| Hydrocortisone | MODERATE | Hydrocortisone is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (hig... |
| Hydroxychloroquine | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Hydroxychloroquine ; concurrent use might inc... |
| Ibandronate | MODERATE | Aspirin (high-dose) is predicted to increase the risk of gastrointestinal irritation when given w... |
| Mefloquine | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Mefloquine ; concurrent use might increase th... |
| Methylprednisolone | MODERATE | Methylprednisolone is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin ... |
| Mometasone | MODERATE | Mometasone is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (high-do... |
| Neomycin | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Neomycin ; concurrent use might increase the ... |
| Netilmicin | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Netilmicin ; concurrent use might increase th... |
| Oxaliplatin | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Oxaliplatin ; concurrent use might increase t... |
| Prednisolone | MODERATE | Prednisolone is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (high-... |
| Quinine | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Quinine ; concurrent use might increase the r... |
| Streptomycin | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Streptomycin ; concurrent use might increase ... |
| Teprotumumab | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Teprotumumab ; concurrent use might increase ... |
| Tobramycin | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Tobramycin ; concurrent use might increase th... |
| Torasemide | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Torasemide ; concurrent use might increase th... |
| Triamcinolone | MODERATE | Triamcinolone is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (high... |
| Vamorolone | MODERATE | Vamorolone is predicted to decrease the concentration of Aspirin (high-dose) and Aspirin (high-do... |
| Vancomycin | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Vancomycin ; concurrent use might increase th... |
| Vinblastine | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Vinblastine ; concurrent use might increase t... |
| Vincristine | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Vincristine ; concurrent use might increase t... |
| Vindesine | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Vindesine ; concurrent use might increase the... |
| Vinorelbine | MODERATE | Aspirin (high-dose) might cause ototoxicity, as can Vinorelbine ; concurrent use might increase t... |
| Aciclovir | LOW | Both Aspirin and Aciclovir can increase the risk of nephrotoxicity. |
| Captopril | LOW | Both Aspirin and Captopril can increase the risk of nephrotoxicity. |
| Cefaclor | LOW | Both Aspirin and Cefaclor can increase the risk of nephrotoxicity. |
| Cefadroxil | LOW | Both Aspirin and Cefadroxil can increase the risk of nephrotoxicity. |
| Cefalexin | LOW | Both Aspirin and Cefalexin can increase the risk of nephrotoxicity. |
| Cefazolin | LOW | Both Aspirin and Cefazolin can increase the risk of nephrotoxicity. |
| Cefepime | LOW | Both Aspirin and Cefepime can increase the risk of nephrotoxicity. |
| Cefixime | LOW | Both Aspirin and Cefixime can increase the risk of nephrotoxicity. |
| Cefotaxime | LOW | Both Aspirin and Cefotaxime can increase the risk of nephrotoxicity. |
| Cefoxitin | LOW | Both Aspirin and Cefoxitin can increase the risk of nephrotoxicity. |
| Cefradine | LOW | Both Aspirin and Cefradine can increase the risk of nephrotoxicity. |
| Ceftaroline | LOW | Both Aspirin and Ceftaroline can increase the risk of nephrotoxicity. |
| Ceftazidime | LOW | Both Aspirin and Ceftazidime can increase the risk of nephrotoxicity. |
| Ceftobiprole | LOW | Both Aspirin and Ceftobiprole can increase the risk of nephrotoxicity. |
| Ceftolozane | LOW | Both Aspirin and Ceftolozane can increase the risk of nephrotoxicity. |
| Ceftriaxone | LOW | Both Aspirin and Ceftriaxone can increase the risk of nephrotoxicity. |
| Cefuroxime | LOW | Both Aspirin and Cefuroxime can increase the risk of nephrotoxicity. |
| Ciclosporin | LOW | Both Aspirin and Ciclosporin can increase the risk of nephrotoxicity. |
| Cidofovir | LOW | Both Aspirin and Cidofovir can increase the risk of nephrotoxicity. |
| Enalapril | LOW | Both Aspirin and Enalapril can increase the risk of nephrotoxicity. |
| Foscarnet | LOW | Both Aspirin and Foscarnet can increase the risk of nephrotoxicity. |
| Fosinopril | LOW | Both Aspirin and Fosinopril can increase the risk of nephrotoxicity. |
| Ganciclovir | LOW | Both Aspirin and Ganciclovir can increase the risk of nephrotoxicity. |
| Ifosfamide | LOW | Both Aspirin and Ifosfamide can increase the risk of nephrotoxicity. |
| Imidapril | LOW | Both Aspirin and Imidapril can increase the risk of nephrotoxicity. |
| Lisinopril | LOW | Both Aspirin and Lisinopril can increase the risk of nephrotoxicity. |
| Lithium | LOW | Both Aspirin and Lithium can increase the risk of nephrotoxicity. |
| Mesalazine | LOW | Both Aspirin and Mesalazine can increase the risk of nephrotoxicity. |
| Pamidronate | LOW | Both Aspirin and Pamidronate can increase the risk of nephrotoxicity. |
| Pentamidine | LOW | Both Aspirin and Pentamidine can increase the risk of nephrotoxicity. |
| Perindopril | LOW | Both Aspirin and Perindopril can increase the risk of nephrotoxicity. |
| Quinapril | LOW | Both Aspirin and Quinapril can increase the risk of nephrotoxicity. |
| Ramipril | LOW | Both Aspirin and Ramipril can increase the risk of nephrotoxicity. |
| Rifampicin | LOW | Both Aspirin and Rifampicin can increase the risk of nephrotoxicity. |
| Streptozocin | LOW | Both Aspirin and Streptozocin can increase the risk of nephrotoxicity. |
| Sulfasalazine | LOW | Both Aspirin and Sulfasalazine can increase the risk of nephrotoxicity. |
| Tacrolimus | LOW | Both Aspirin and Tacrolimus can increase the risk of nephrotoxicity. |
| Tenofovir disoproxil | LOW | Both Aspirin and Tenofovir disoproxil can increase the risk of nephrotoxicity. |
| Trandolapril | LOW | Both Aspirin and Trandolapril can increase the risk of nephrotoxicity. |
| Trimethoprim | LOW | Both Aspirin and Trimethoprim can increase the risk of nephrotoxicity. |
| Valaciclovir | LOW | Both Aspirin and Valaciclovir can increase the risk of nephrotoxicity. |
| Valganciclovir | LOW | Both Aspirin and Valganciclovir can increase the risk of nephrotoxicity. |
| Voclosporin | LOW | Both Aspirin and Voclosporin can increase the risk of nephrotoxicity. |
| Zoledronate | LOW | Both Aspirin and Zoledronate can increase the risk of nephrotoxicity. |
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