Bisoprolol Drug Interactions
194Total Interactions
16Severe
6Moderate
1Mild
| Drug | Severity | Summary |
|---|---|---|
| Adrenaline/epinephrine | SEVERE | Bisoprolol is predicted to increase the risk of hypertension and bradycardia when given with Adre... |
| Aminophylline | SEVERE | Bisoprolol is predicted to increase the risk of bronchospasm when given with Aminophylline. Manuf... |
| Amiodarone | SEVERE | Amiodarone is predicted to increase the risk of cardiovascular adverse effects when given with Bi... |
| Diltiazem | SEVERE | Diltiazem is predicted to increase the risk of cardiodepression when given with Bisoprolol. Manuf... |
| Disopyramide | SEVERE | Disopyramide is predicted to increase the risk of cardiovascular adverse effects when given with ... |
| Dronedarone | SEVERE | Dronedarone is predicted to increase the risk of cardiovascular adverse effects when given with B... |
| Ergometrine | SEVERE | Bisoprolol is predicted to increase the risk of peripheral vasoconstriction when given with Ergom... |
| Flecainide | SEVERE | Flecainide is predicted to increase the risk of cardiovascular adverse effects when given with Bi... |
| Lidocaine | SEVERE | Lidocaine is predicted to increase the risk of cardiovascular adverse effects when given with Bis... |
| Mavacamten | SEVERE | Mavacamten can cause negative inotropic effects, as can Bisoprolol. Manufacturer advises monitor. |
| Mefloquine | SEVERE | Mefloquine is predicted to increase the risk of bradycardia when given with Bisoprolol. Manufactu... |
| Mexiletine | SEVERE | Mexiletine potentially increases the risk of cardiovascular adverse effects when given with Bisop... |
| Noradrenaline/norepinephrine | SEVERE | Bisoprolol is predicted to increase the risk of hypertension and bradycardia when given with Nora... |
| Propafenone | SEVERE | Propafenone is predicted to increase the risk of cardiovascular adverse effects when given with B... |
| Theophylline | SEVERE | Bisoprolol is predicted to increase the risk of bronchospasm when given with Theophylline. Manufa... |
| Verapamil | SEVERE | Verapamil increases the risk of cardiovascular adverse effects when given with Bisoprolol. Manufa... |
| Dobutamine | MODERATE | Bisoprolol increases the risk of hypertension and bradycardia when given with Dobutamine. Manufac... |
| Enzalutamide | MODERATE | Enzalutamide is predicted to affect the exposure to Bisoprolol. Manufacturer advises use with cau... |
| Lanreotide | MODERATE | Bisoprolol is predicted to increase the risk of bradycardia when given with Lanreotide. Manufactu... |
| Omega-3-acid ethyl esters | MODERATE | Omega-3-acid ethyl esters might enhance the blood pressure-lowering effects of Bisoprolol. Manufa... |
| Phenobarbital | MODERATE | Phenobarbital is predicted to decrease the exposure to Bisoprolol. Manufacturer makes no recommen... |
| Primidone | MODERATE | Primidone is predicted to decrease the exposure to Bisoprolol. Manufacturer makes no recommendation. |
| Rifampicin | MILD | Rifampicin slightly decreases the exposure to Bisoprolol. Manufacturer makes no recommendation. |
| Alcohol | LOW | Both Bisoprolol and Alcohol can increase the risk of hypotension. |
| Alectinib | LOW | Both Bisoprolol and Alectinib can increase the risk of bradycardia. |
| Alfentanil | LOW | Both Bisoprolol and Alfentanil can increase the risk of bradycardia. |
| Alfuzosin | LOW | Both Bisoprolol and Alfuzosin can increase the risk of hypotension. |
| Aliskiren | LOW | Both Bisoprolol and Aliskiren can increase the risk of hypotension. |
| Alprostadil | LOW | Both Bisoprolol and Alprostadil can increase the risk of hypotension. |
| Amantadine | LOW | Both Bisoprolol and Amantadine can increase the risk of hypotension. |
| Amitriptyline | LOW | Both Bisoprolol and Amitriptyline can increase the risk of hypotension. |
| Amlodipine | LOW | Both Bisoprolol and Amlodipine can increase the risk of hypotension. |
| Apomorphine | LOW | Both Bisoprolol and Apomorphine can increase the risk of hypotension. |
| Apraclonidine | LOW | Both Bisoprolol and Apraclonidine can increase the risk of bradycardia. |
| Aripiprazole | LOW | Both Bisoprolol and Aripiprazole can increase the risk of hypotension. |
| Asenapine | LOW | Both Bisoprolol and Asenapine can increase the risk of hypotension. |
| Avanafil | LOW | Both Bisoprolol and Avanafil can increase the risk of hypotension. |
| Azilsartan | LOW | Both Bisoprolol and Azilsartan can increase the risk of hypotension. |
| Baclofen | LOW | Both Bisoprolol and Baclofen can increase the risk of hypotension. |
| Bendroflumethiazide | LOW | Both Bisoprolol and Bendroflumethiazide can increase the risk of hypotension. |
| Benperidol | LOW | Both Bisoprolol and Benperidol can increase the risk of hypotension. |
| Bortezomib | LOW | Both Bisoprolol and Bortezomib can increase the risk of hypotension. |
| Brigatinib | LOW | Both Bisoprolol and Brigatinib can increase the risk of bradycardia. |
| Brimonidine | LOW | Both Bisoprolol and Brimonidine can increase the risk of bradycardia. |
| Bromocriptine | LOW | Both Bisoprolol and Bromocriptine can increase the risk of hypotension. |
| Bumetanide | LOW | Both Bisoprolol and Bumetanide can increase the risk of hypotension. |
| Cabergoline | LOW | Both Bisoprolol and Cabergoline can increase the risk of hypotension. |
| Canagliflozin | LOW | Both Bisoprolol and Canagliflozin can increase the risk of hypotension. |
| Candesartan | LOW | Both Bisoprolol and Candesartan can increase the risk of hypotension. |
| Captopril | LOW | Both Bisoprolol and Captopril can increase the risk of hypotension. |
| Cariprazine | LOW | Both Bisoprolol and Cariprazine can increase the risk of hypotension. |
| Carvedilol | LOW | Both Bisoprolol and Carvedilol can increase the risk of bradycardia. |
| Ceritinib | LOW | Both Bisoprolol and Ceritinib can increase the risk of bradycardia. |
| Chlorothiazide | LOW | Both Bisoprolol and Chlorothiazide can increase the risk of hypotension. |
| Chlorpromazine | LOW | Both Bisoprolol and Chlorpromazine can increase the risk of hypotension. |
| Chlortalidone | LOW | Both Bisoprolol and Chlortalidone can increase the risk of hypotension. |
| Clomipramine | LOW | Both Bisoprolol and Clomipramine can increase the risk of hypotension. |
| Clonidine | LOW | Both Bisoprolol and Clonidine can increase the risk of bradycardia. |
| Clozapine | LOW | Both Bisoprolol and Clozapine can increase the risk of hypotension. |
| Crizotinib | LOW | Both Bisoprolol and Crizotinib can increase the risk of bradycardia. |
| Dapagliflozin | LOW | Both Bisoprolol and Dapagliflozin can increase the risk of hypotension. |
| Desflurane | LOW | Both Bisoprolol and Desflurane can increase the risk of hypotension. |
| Diazoxide | LOW | Both Bisoprolol and Diazoxide can increase the risk of hypotension. |
| Digoxin | LOW | Both Bisoprolol and Digoxin can increase the risk of bradycardia. |
| Dipyridamole | LOW | Both Bisoprolol and Dipyridamole can increase the risk of hypotension. |
| Donepezil | LOW | Both Bisoprolol and Donepezil can increase the risk of bradycardia. |
| Dosulepin | LOW | Both Bisoprolol and Dosulepin can increase the risk of hypotension. |
| Doxazosin | LOW | Both Bisoprolol and Doxazosin can increase the risk of hypotension. |
| Doxepin | LOW | Both Bisoprolol and Doxepin can increase the risk of hypotension. |
| Droperidol | LOW | Both Bisoprolol and Droperidol can increase the risk of hypotension. |
| Empagliflozin | LOW | Both Bisoprolol and Empagliflozin can increase the risk of hypotension. |
| Enalapril | LOW | Both Bisoprolol and Enalapril can increase the risk of hypotension. |
| Eplerenone | LOW | Both Bisoprolol and Eplerenone can increase the risk of hypotension. |
| Epoprostenol | LOW | Both Bisoprolol and Epoprostenol can increase the risk of hypotension. |
| Eprosartan | LOW | Both Bisoprolol and Eprosartan can increase the risk of hypotension. |
| Ertugliflozin | LOW | Both Bisoprolol and Ertugliflozin can increase the risk of hypotension. |
| Esketamine | LOW | Both Bisoprolol and Esketamine can increase the risk of hypotension. |
| Etomidate | LOW | Both Bisoprolol and Etomidate can increase the risk of hypotension. |
| Etrasimod | LOW | Both Bisoprolol and Etrasimod can increase the risk of bradycardia. |
| Felodipine | LOW | Both Bisoprolol and Felodipine can increase the risk of hypotension. |
| Fentanyl | LOW | Both Bisoprolol and Fentanyl can increase the risk of bradycardia. |
| Finerenone | LOW | Both Bisoprolol and Finerenone can increase the risk of hypotension. |
| Fingolimod | LOW | Both Bisoprolol and Fingolimod can increase the risk of bradycardia. |
| Flupentixol | LOW | Both Bisoprolol and Flupentixol can increase the risk of hypotension. |
| Fosinopril | LOW | Both Bisoprolol and Fosinopril can increase the risk of hypotension. |
| Foslevodopa | LOW | Both Bisoprolol and Foslevodopa can increase the risk of hypotension. |
| Furosemide | LOW | Both Bisoprolol and Furosemide can increase the risk of hypotension. |
| Galantamine | LOW | Both Bisoprolol and Galantamine can increase the risk of bradycardia. |
| Glyceryl trinitrate | LOW | Both Bisoprolol and Glyceryl trinitrate can increase the risk of hypotension. |
| Guanfacine | LOW | Both Bisoprolol and Guanfacine can increase the risk of hypotension. |
| Haloperidol | LOW | Both Bisoprolol and Haloperidol can increase the risk of hypotension. |
| Hydralazine | LOW | Both Bisoprolol and Hydralazine can increase the risk of hypotension. |
| Hydrochlorothiazide | LOW | Both Bisoprolol and Hydrochlorothiazide can increase the risk of hypotension. |
| Hydroflumethiazide | LOW | Both Bisoprolol and Hydroflumethiazide can increase the risk of hypotension. |
| Iloprost | LOW | Both Bisoprolol and Iloprost can increase the risk of hypotension. |
| Imidapril | LOW | Both Bisoprolol and Imidapril can increase the risk of hypotension. |
| Imipramine | LOW | Both Bisoprolol and Imipramine can increase the risk of hypotension. |
| Indapamide | LOW | Both Bisoprolol and Indapamide can increase the risk of hypotension. |
| Indoramin | LOW | Both Bisoprolol and Indoramin can increase the risk of hypotension. |
| Irbesartan | LOW | Both Bisoprolol and Irbesartan can increase the risk of hypotension. |
| Isocarboxazid | LOW | Both Bisoprolol and Isocarboxazid can increase the risk of hypotension. |
| Isoflurane | LOW | Both Bisoprolol and Isoflurane can increase the risk of hypotension. |
| Isosorbide dinitrate | LOW | Both Bisoprolol and Isosorbide dinitrate can increase the risk of hypotension. |
| Isosorbide mononitrate | LOW | Both Bisoprolol and Isosorbide mononitrate can increase the risk of hypotension. |
| Ivabradine | LOW | Both Bisoprolol and Ivabradine can increase the risk of bradycardia. |
| Ketamine | LOW | Both Bisoprolol and Ketamine can increase the risk of hypotension. |
| Labetalol | LOW | Both Bisoprolol and Labetalol can increase the risk of bradycardia. |
| Lacidipine | LOW | Both Bisoprolol and Lacidipine can increase the risk of hypotension. |
| Lercanidipine | LOW | Both Bisoprolol and Lercanidipine can increase the risk of hypotension. |
| Levobunolol | LOW | Both Bisoprolol and Levobunolol can increase the risk of bradycardia. |
| Levodopa | LOW | Both Bisoprolol and Levodopa can increase the risk of hypotension. |
| Levomepromazine | LOW | Both Bisoprolol and Levomepromazine can increase the risk of hypotension. |
| Lisinopril | LOW | Both Bisoprolol and Lisinopril can increase the risk of hypotension. |
| Lofepramine | LOW | Both Bisoprolol and Lofepramine can increase the risk of hypotension. |
| Lofexidine | LOW | Both Bisoprolol and Lofexidine can increase the risk of hypotension. |
| Losartan | LOW | Both Bisoprolol and Losartan can increase the risk of hypotension. |
| Loxapine | LOW | Both Bisoprolol and Loxapine can increase the risk of hypotension. |
| Lurasidone | LOW | Both Bisoprolol and Lurasidone can increase the risk of hypotension. |
| Methoxyflurane | LOW | Both Bisoprolol and Methoxyflurane can increase the risk of hypotension. |
| Methyldopa | LOW | Both Bisoprolol and Methyldopa can increase the risk of hypotension. |
| Metolazone | LOW | Both Bisoprolol and Metolazone can increase the risk of hypotension. |
| Minoxidil | LOW | Both Bisoprolol and Minoxidil can increase the risk of hypotension. |
| Moxonidine | LOW | Both Bisoprolol and Moxonidine can increase the risk of hypotension. |
| Nadolol | LOW | Both Bisoprolol and Nadolol can increase the risk of bradycardia. |
| Neostigmine | LOW | Both Bisoprolol and Neostigmine can increase the risk of bradycardia. |
| Nicardipine | LOW | Both Bisoprolol and Nicardipine can increase the risk of hypotension. |
| Nicorandil | LOW | Both Bisoprolol and Nicorandil can increase the risk of hypotension. |
| Nifedipine | LOW | Both Bisoprolol and Nifedipine can increase the risk of hypotension. |
| Nimodipine | LOW | Both Bisoprolol and Nimodipine can increase the risk of hypotension. |
| Nitroprusside | LOW | Both Bisoprolol and Nitroprusside can increase the risk of hypotension. |
| Nitrous oxide | LOW | Both Bisoprolol and Nitrous oxide can increase the risk of hypotension. |
| Nortriptyline | LOW | Both Bisoprolol and Nortriptyline can increase the risk of hypotension. |
| Olanzapine | LOW | Both Bisoprolol and Olanzapine can increase the risk of hypotension. |
| Olmesartan | LOW | Both Bisoprolol and Olmesartan can increase the risk of hypotension. |
| Ozanimod | LOW | Both Bisoprolol and Ozanimod can increase the risk of bradycardia. |
| Paliperidone | LOW | Both Bisoprolol and Paliperidone can increase the risk of hypotension. |
| Pasireotide | LOW | Both Bisoprolol and Pasireotide can increase the risk of bradycardia. |
| Pericyazine | LOW | Both Bisoprolol and Pericyazine can increase the risk of hypotension. |
| Perindopril | LOW | Both Bisoprolol and Perindopril can increase the risk of hypotension. |
| Phenelzine | LOW | Both Bisoprolol and Phenelzine can increase the risk of hypotension. |
| Pimozide | LOW | Both Bisoprolol and Pimozide can increase the risk of hypotension. |
| Pindolol | LOW | Both Bisoprolol and Pindolol can increase the risk of bradycardia. |
| Ponesimod | LOW | Both Bisoprolol and Ponesimod can increase the risk of bradycardia. |
| Pramipexole | LOW | Both Bisoprolol and Pramipexole can increase the risk of hypotension. |
| Prazosin | LOW | Both Bisoprolol and Prazosin can increase the risk of hypotension. |
| Prochlorperazine | LOW | Both Bisoprolol and Prochlorperazine can increase the risk of hypotension. |
| Promazine | LOW | Both Bisoprolol and Promazine can increase the risk of hypotension. |
| Propofol | LOW | Both Bisoprolol and Propofol can increase the risk of bradycardia. |
| Propranolol | LOW | Both Bisoprolol and Propranolol can increase the risk of bradycardia. |
| Pyridostigmine | LOW | Both Bisoprolol and Pyridostigmine can increase the risk of bradycardia. |
| Quetiapine | LOW | Both Bisoprolol and Quetiapine can increase the risk of hypotension. |
| Quinagolide | LOW | Both Bisoprolol and Quinagolide can increase the risk of hypotension. |
| Quinapril | LOW | Both Bisoprolol and Quinapril can increase the risk of hypotension. |
| Ramipril | LOW | Both Bisoprolol and Ramipril can increase the risk of hypotension. |
| Remifentanil | LOW | Both Bisoprolol and Remifentanil can increase the risk of bradycardia. |
| Riociguat | LOW | Both Bisoprolol and Riociguat can increase the risk of hypotension. |
| Risperidone | LOW | Both Bisoprolol and Risperidone can increase the risk of hypotension. |
| Rivastigmine | LOW | Both Bisoprolol and Rivastigmine can increase the risk of bradycardia. |
| Ropinirole | LOW | Both Bisoprolol and Ropinirole can increase the risk of hypotension. |
| Rotigotine | LOW | Both Bisoprolol and Rotigotine can increase the risk of hypotension. |
| Sacubitril | LOW | Both Bisoprolol and Sacubitril can increase the risk of hypotension. |
| Sapropterin | LOW | Both Bisoprolol and Sapropterin can increase the risk of hypotension. |
| Selegiline | LOW | Both Bisoprolol and Selegiline can increase the risk of bradycardia. |
| Sevoflurane | LOW | Both Bisoprolol and Sevoflurane can increase the risk of hypotension. |
| Sildenafil | LOW | Both Bisoprolol and Sildenafil can increase the risk of hypotension. |
| Siponimod | LOW | Both Bisoprolol and Siponimod can increase the risk of bradycardia. |
| Sodium oxybate | LOW | Both Bisoprolol and Sodium oxybate can increase the risk of hypotension. |
| Sotalol | LOW | Both Bisoprolol and Sotalol can increase the risk of bradycardia. |
| Sparsentan | LOW | Both Bisoprolol and Sparsentan can increase the risk of hypotension. |
| Spironolactone | LOW | Both Bisoprolol and Spironolactone can increase the risk of hypotension. |
| Sufentanil | LOW | Both Bisoprolol and Sufentanil can increase the risk of bradycardia. |
| Sulpiride | LOW | Both Bisoprolol and Sulpiride can increase the risk of hypotension. |
| Suxamethonium | LOW | Both Bisoprolol and Suxamethonium can increase the risk of bradycardia. |
| Tadalafil | LOW | Both Bisoprolol and Tadalafil can increase the risk of hypotension. |
| Tamsulosin | LOW | Both Bisoprolol and Tamsulosin can increase the risk of hypotension. |
| Telmisartan | LOW | Both Bisoprolol and Telmisartan can increase the risk of hypotension. |
| Terazosin | LOW | Both Bisoprolol and Terazosin can increase the risk of hypotension. |
| Thalidomide | LOW | Both Bisoprolol and Thalidomide can increase the risk of bradycardia. |
| Thiopental | LOW | Both Bisoprolol and Thiopental can increase the risk of hypotension. |
| Ticagrelor | LOW | Both Bisoprolol and Ticagrelor can increase the risk of bradycardia. |
| Timolol | LOW | Both Bisoprolol and Timolol can increase the risk of bradycardia. |
| Tizanidine | LOW | Both Bisoprolol and Tizanidine can increase the risk of bradycardia. |
| Torasemide | LOW | Both Bisoprolol and Torasemide can increase the risk of hypotension. |
| Trandolapril | LOW | Both Bisoprolol and Trandolapril can increase the risk of hypotension. |
| Tranylcypromine | LOW | Both Bisoprolol and Tranylcypromine can increase the risk of hypotension. |
| Treprostinil | LOW | Both Bisoprolol and Treprostinil can increase the risk of hypotension. |
| Trifluoperazine | LOW | Both Bisoprolol and Trifluoperazine can increase the risk of hypotension. |
| Trimipramine | LOW | Both Bisoprolol and Trimipramine can increase the risk of hypotension. |
| Valsartan | LOW | Both Bisoprolol and Valsartan can increase the risk of hypotension. |
| Vardenafil | LOW | Both Bisoprolol and Vardenafil can increase the risk of hypotension. |
| Vericiguat | LOW | Both Bisoprolol and Vericiguat can increase the risk of hypotension. |
| Vernakalant | LOW | Both Bisoprolol and Vernakalant can increase the risk of hypotension. |
| Xipamide | LOW | Both Bisoprolol and Xipamide can increase the risk of hypotension. |
| Zuclopenthixol | LOW | Both Bisoprolol and Zuclopenthixol can increase the risk of hypotension. |
Check Bisoprolol against your patient's full medication list
InteractRx checks all drug combinations at once — built for GP surgery pharmacists.
Use the Free Checker