Clopidogrel Drug Interactions
129Total Interactions
112Severe
17Moderate
0Mild
| Drug | Severity | Summary |
|---|---|---|
| Acalabrutinib | SEVERE | Both Clopidogrel and Acalabrutinib can increase the risk of bleeding. |
| Aceclofenac | SEVERE | Both Clopidogrel and Aceclofenac can increase the risk of bleeding. |
| Acenocoumarol | SEVERE | Acenocoumarol causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of dev... |
| Alprostadil | SEVERE | Both Clopidogrel and Alprostadil can increase the risk of bleeding. |
| Alteplase | SEVERE | Alteplase causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of develop... |
| Anagrelide | SEVERE | Both Clopidogrel and Anagrelide can increase the risk of bleeding. |
| Apixaban | SEVERE | Apixaban causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of developi... |
| Argatroban | SEVERE | Argatroban causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of develo... |
| Asparaginase | SEVERE | Asparaginase causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of deve... |
| Aspirin | SEVERE | Both Clopidogrel and Aspirin can increase the risk of bleeding. |
| Avapritinib | SEVERE | Clopidogrel might increase the risk of bleeding when given with Avapritinib. Manufacturer advises... |
| Axitinib | SEVERE | Both Clopidogrel and Axitinib can increase the risk of bleeding. |
| Bemiparin | SEVERE | Bemiparin causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of develop... |
| Benzydamine | SEVERE | Both Clopidogrel and Benzydamine can increase the risk of bleeding. |
| Bevacizumab | SEVERE | Clopidogrel causes bleeding, as can Bevacizumab ; concurrent use might increase the risk of devel... |
| Bivalirudin | SEVERE | Bivalirudin causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of devel... |
| Bosutinib | SEVERE | Both Clopidogrel and Bosutinib can increase the risk of bleeding. |
| Bromfenac | SEVERE | Both Clopidogrel and Bromfenac can increase the risk of bleeding. |
| Cabozantinib | SEVERE | Clopidogrel causes bleeding, as can Cabozantinib ; concurrent use might increase the risk of deve... |
| Cangrelor | SEVERE | Both Clopidogrel and Cangrelor can increase the risk of bleeding. |
| Caplacizumab | SEVERE | Clopidogrel causes bleeding, as can Caplacizumab ; concurrent use might increase the risk of deve... |
| Celecoxib | SEVERE | Both Clopidogrel and Celecoxib can increase the risk of bleeding. |
| Cilostazol | SEVERE | Both Clopidogrel and Cilostazol can increase the risk of bleeding. |
| Citalopram | SEVERE | Both Clopidogrel and Citalopram can increase the risk of bleeding. |
| Cobicistat | SEVERE | Cobicistat is predicted to decrease the concentration of the active metabolite of Clopidogrel. Ma... |
| Cobimetinib | SEVERE | Clopidogrel causes bleeding, as can Cobimetinib ; concurrent use might increase the risk of devel... |
| Crisantaspase | SEVERE | Crisantaspase causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of dev... |
| Dabigatran | SEVERE | Dabigatran causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of develo... |
| Dalteparin | SEVERE | Dalteparin causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of develo... |
| Danaparoid | SEVERE | Danaparoid causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of develo... |
| Dapoxetine | SEVERE | Both Clopidogrel and Dapoxetine can increase the risk of bleeding. |
| Dasatinib | SEVERE | Both Clopidogrel and Dasatinib can increase the risk of bleeding. |
| Dexketoprofen | SEVERE | Both Clopidogrel and Dexketoprofen can increase the risk of bleeding. |
| Diclofenac | SEVERE | Both Clopidogrel and Diclofenac can increase the risk of bleeding. |
| Dipyridamole | SEVERE | Both Clopidogrel and Dipyridamole can increase the risk of bleeding. |
| Donanemab | SEVERE | Donanemab can increase the risk of bleeding when given with Clopidogrel. Manufacturer makes no re... |
| Duloxetine | SEVERE | Both Clopidogrel and Duloxetine can increase the risk of bleeding. |
| Edoxaban | SEVERE | Edoxaban causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of developi... |
| Enoxaparin | SEVERE | Enoxaparin causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of develo... |
| Enzalutamide | SEVERE | Clopidogrel moderately increases the exposure to Enzalutamide. Manufacturer advises avoid or adju... |
| Epoprostenol | SEVERE | Both Clopidogrel and Epoprostenol can increase the risk of bleeding. |
| Eptifibatide | SEVERE | Eptifibatide causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of deve... |
| Escitalopram | SEVERE | Both Clopidogrel and Escitalopram can increase the risk of bleeding. |
| Etodolac | SEVERE | Both Clopidogrel and Etodolac can increase the risk of bleeding. |
| Etoricoxib | SEVERE | Both Clopidogrel and Etoricoxib can increase the risk of bleeding. |
| Etrasimod | SEVERE | Clopidogrel are predicted to increases the exposure to Etrasimod. Manufacturer advises avoid in p... |
| Fluconazole | SEVERE | Fluconazole is predicted to decrease the efficacy of Clopidogrel. Manufacturer advises avoid. |
| Fluoxetine | SEVERE | Fluoxetine is predicted to decrease the efficacy of Clopidogrel. Manufacturer advises avoid. |
| Flurbiprofen | SEVERE | Both Clopidogrel and Flurbiprofen can increase the risk of bleeding. |
| Fluvoxamine | SEVERE | Fluvoxamine is predicted to decrease the efficacy of Clopidogrel. Manufacturer advises avoid. |
| Fondaparinux | SEVERE | Fondaparinux causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of deve... |
| Grapefruit | SEVERE | Grapefruit juice markedly decreases the exposure to Clopidogrel. Manufacturer makes no recommenda... |
| Heparin | SEVERE | Heparin causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of developin... |
| Ibrutinib | SEVERE | Both Clopidogrel and Ibrutinib can increase the risk of bleeding. |
| Ibuprofen | SEVERE | Both Clopidogrel and Ibuprofen can increase the risk of bleeding. |
| Icosapent | SEVERE | Both Clopidogrel and Icosapent can increase the risk of bleeding. |
| Iloprost | SEVERE | Both Clopidogrel and Iloprost can increase the risk of bleeding. |
| Imatinib | SEVERE | Both Clopidogrel and Imatinib can increase the risk of bleeding. |
| Indometacin | SEVERE | Both Clopidogrel and Indometacin can increase the risk of bleeding. |
| Inotersen | SEVERE | Clopidogrel causes bleeding, as can Inotersen ; concurrent use might increase the risk of develop... |
| Ketoprofen | SEVERE | Both Clopidogrel and Ketoprofen can increase the risk of bleeding. |
| Ketorolac | SEVERE | Both Clopidogrel and Ketorolac can increase the risk of bleeding. |
| Lecanemab | SEVERE | Lecanemab can increase the risk of bleeding when given with Clopidogrel. Manufacturer makes no re... |
| Lenvatinib | SEVERE | Both Clopidogrel and Lenvatinib can increase the risk of bleeding. |
| Mefenamic acid | SEVERE | Both Clopidogrel and Mefenamic acid can increase the risk of bleeding. |
| Meloxicam | SEVERE | Both Clopidogrel and Meloxicam can increase the risk of bleeding. |
| Nabumetone | SEVERE | Both Clopidogrel and Nabumetone can increase the risk of bleeding. |
| Naproxen | SEVERE | Both Clopidogrel and Naproxen can increase the risk of bleeding. |
| Nicotinic acid | SEVERE | Nicotinic acid causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of de... |
| Nintedanib | SEVERE | Both Clopidogrel and Nintedanib can increase the risk of bleeding. |
| Nirmatrelvir | SEVERE | Nirmatrelvir boosted with ritonavir is predicted to decrease the concentration of Clopidogrel. Ma... |
| Omega-3-acid ethyl esters | SEVERE | Both Clopidogrel and Omega-3-acid ethyl esters can increase the risk of bleeding. |
| Paclitaxel | SEVERE | Clopidogrel is predicted to increase the concentration of Paclitaxel. Manufacturer advises caution. |
| Parecoxib | SEVERE | Both Clopidogrel and Parecoxib can increase the risk of bleeding. |
| Paroxetine | SEVERE | Both Clopidogrel and Paroxetine can increase the risk of bleeding. |
| Pazopanib | SEVERE | Both Clopidogrel and Pazopanib can increase the risk of bleeding. |
| Pegaspargase | SEVERE | Pegaspargase causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of deve... |
| Pentosan | SEVERE | Pentosan causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of developi... |
| Phenazone | SEVERE | Both Clopidogrel and Phenazone can increase the risk of bleeding. |
| Phenindione | SEVERE | Phenindione causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of devel... |
| Pioglitazone | SEVERE | Clopidogrel increases the exposure to Pioglitazone. Manufacturer advises monitor blood glucose an... |
| Piroxicam | SEVERE | Both Clopidogrel and Piroxicam can increase the risk of bleeding. |
| Ponatinib | SEVERE | Both Clopidogrel and Ponatinib can increase the risk of bleeding. |
| Prasugrel | SEVERE | Both Clopidogrel and Prasugrel can increase the risk of bleeding. |
| Ranibizumab | SEVERE | Clopidogrel causes bleeding, as can Ranibizumab ; concurrent use might increase the risk of devel... |
| Regorafenib | SEVERE | Both Clopidogrel and Regorafenib can increase the risk of bleeding. |
| Repaglinide | SEVERE | Clopidogrel increases the exposure to Repaglinide. Manufacturer advises avoid. |
| Rivaroxaban | SEVERE | Rivaroxaban causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of devel... |
| Ruxolitinib | SEVERE | Clopidogrel causes bleeding, as can Ruxolitinib ; concurrent use might increase the risk of devel... |
| Selumetinib | SEVERE | Selumetinib might increase the risk of bleeding when given with Clopidogrel. Manufacturer advises... |
| Sertraline | SEVERE | Both Clopidogrel and Sertraline can increase the risk of bleeding. |
| Sorafenib | SEVERE | Both Clopidogrel and Sorafenib can increase the risk of bleeding. |
| Streptokinase | SEVERE | Streptokinase causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of dev... |
| Sulindac | SEVERE | Both Clopidogrel and Sulindac can increase the risk of bleeding. |
| Sunitinib | SEVERE | Both Clopidogrel and Sunitinib can increase the risk of bleeding. |
| Tenecteplase | SEVERE | Tenecteplase causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of deve... |
| Tenoxicam | SEVERE | Both Clopidogrel and Tenoxicam can increase the risk of bleeding. |
| Tiaprofenic acid | SEVERE | Both Clopidogrel and Tiaprofenic acid can increase the risk of bleeding. |
| Ticagrelor | SEVERE | Both Clopidogrel and Ticagrelor can increase the risk of bleeding. |
| Tinzaparin | SEVERE | Tinzaparin causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of develo... |
| Tirofiban | SEVERE | Tirofiban causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of develop... |
| Tolfenamic acid | SEVERE | Both Clopidogrel and Tolfenamic acid can increase the risk of bleeding. |
| Trametinib | SEVERE | Clopidogrel causes bleeding, as can Trametinib ; concurrent use might increase the risk of develo... |
| Trastuzumab emtansine | SEVERE | Clopidogrel causes bleeding, as can Trastuzumab emtansine ; concurrent use might increase the ris... |
| Treprostinil | SEVERE | Both Clopidogrel and Treprostinil can increase the risk of bleeding. |
| Tucatinib | SEVERE | Clopidogrel is predicted to increase the exposure to Tucatinib. Manufacturer advises avoid or adj... |
| Urokinase | SEVERE | Urokinase causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of develop... |
| Venlafaxine | SEVERE | Both Clopidogrel and Venlafaxine can increase the risk of bleeding. |
| Volanesorsen | SEVERE | Clopidogrel causes bleeding, as can Volanesorsen ; concurrent use might increase the risk of deve... |
| Vortioxetine | SEVERE | Both Clopidogrel and Vortioxetine can increase the risk of bleeding. |
| Warfarin | SEVERE | Warfarin causes bleeding, as can Clopidogrel ; concurrent use might increase the risk of developi... |
| Zanubrutinib | SEVERE | Both Clopidogrel and Zanubrutinib can increase the risk of bleeding. |
| Alitretinoin | MODERATE | Clopidogrel is predicted to increase the exposure to Alitretinoin. Manufacturer advises adjust Al... |
| Apalutamide | MODERATE | Clopidogrel is predicted to increase the exposure to Apalutamide and Apalutamide is predicted to ... |
| Bupropion | MODERATE | Clopidogrel slightly increases the exposure to Bupropion. Manufacturer advises caution. |
| Cenobamate | MODERATE | Cenobamate is predicted to decrease the efficacy of Clopidogrel. Manufacturer advises avoid. |
| Dabrafenib | MODERATE | Clopidogrel is predicted to increase the exposure to Dabrafenib. Manufacturer advises caution. |
| Esomeprazole | MODERATE | Esomeprazole is predicted to decrease the efficacy of Clopidogrel. Manufacturer advises avoid. |
| Fedratinib | MODERATE | Fedratinib is predicted to decrease the efficacy of Clopidogrel. Manufacturer advises avoid. |
| Moclobemide | MODERATE | Moclobemide is predicted to decrease the efficacy of Clopidogrel. Manufacturer advises avoid. |
| Montelukast | MODERATE | Clopidogrel is predicted to moderately increase the exposure to Montelukast. Manufacturer advises... |
| Omeprazole | MODERATE | Omeprazole is predicted to decrease the efficacy of Clopidogrel. Manufacturer advises avoid. |
| Ozanimod | MODERATE | Clopidogrel is predicted to increase the exposure to the active metabolites of Ozanimod. Manufact... |
| Rifampicin | MODERATE | Rifampicin moderately increases the exposure to the active metabolite of Clopidogrel. Manufacture... |
| Ritonavir | MODERATE | Ritonavir might decrease the efficacy of Clopidogrel. Manufacturer advises avoid. |
| Rosuvastatin | MODERATE | Clopidogrel increases the exposure to Rosuvastatin. Manufacturer advises adjust Rosuvastatin dose. |
| Roxadustat | MODERATE | Clopidogrel is predicted to increase the exposure to Roxadustat. Manufacturer advises monitor hae... |
| Selexipag | MODERATE | Clopidogrel is predicted to increase the exposure to Selexipag. Manufacturer advises adjust Selex... |
| Voriconazole | MODERATE | Voriconazole is predicted to decrease the efficacy of Clopidogrel. Manufacturer advises avoid. |
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