Doxycycline Drug Interactions
91Total Interactions
14Severe
22Moderate
0Mild
| Drug | Severity | Summary |
|---|---|---|
| Acenocoumarol | SEVERE | Doxycycline increases the anticoagulant effect of Acenocoumarol. Manufacturer advises monitor INR. |
| Acitretin | SEVERE | Acitretin increases the risk of benign intracranial hypertension when given with Doxycycline. Man... |
| Alcohol | SEVERE | Alcohol -induced liver disease increases the risk of hepatotoxicity in those taking Doxycycline. ... |
| Alitretinoin | SEVERE | Alitretinoin increases the risk of benign intracranial hypertension when given with Doxycycline. ... |
| Bemiparin | SEVERE | Doxycycline might increase the risk of hepatotoxicity when given with Bemiparin (high-dose). Manu... |
| Ciclosporin | SEVERE | Doxycycline is predicted to increase the concentration of Ciclosporin. Manufacturer advises monitor. |
| Dalteparin | SEVERE | Doxycycline might increase the risk of hepatotoxicity when given with Dalteparin (high-dose). Man... |
| Enoxaparin | SEVERE | Doxycycline might increase the risk of hepatotoxicity when given with Enoxaparin (high-dose). Man... |
| Isotretinoin | SEVERE | Isotretinoin increases the risk of benign intracranial hypertension when given with Doxycycline. ... |
| Lithium | SEVERE | Doxycycline is predicted to increase the risk of Lithium (Lithium carbonate, Lithium citrate) tox... |
| Phenindione | SEVERE | Doxycycline is predicted to increase the anticoagulant effect of Phenindione. Manufacturer advise... |
| Tinzaparin | SEVERE | Doxycycline might increase the risk of hepatotoxicity when given with Tinzaparin (high-dose). Man... |
| Tretinoin | SEVERE | Tretinoin increases the risk of benign intracranial hypertension when given with Doxycycline. Man... |
| Warfarin | SEVERE | Doxycycline increases the anticoagulant effect of Warfarin. Manufacturer advises monitor INR. |
| Antacids | MODERATE | oral Antacids greatly decrease the absorption of oral Doxycycline. Manufacturer advises separate ... |
| Bismuth | MODERATE | oral Bismuth greatly decreases the absorption of oral Doxycycline. Manufacturer advises separate ... |
| Calcium acetate | MODERATE | oral Calcium acetate is predicted to decrease the absorption of oral Doxycycline. Manufacturer ad... |
| Calcium carbonate | MODERATE | oral Calcium carbonate is predicted to decrease the absorption of oral Doxycycline. Manufacturer ... |
| Calcium chloride | MODERATE | oral Calcium chloride is predicted to decrease the absorption of oral Doxycycline. Manufacturer a... |
| Calcium gluconate | MODERATE | oral Calcium gluconate is predicted to decrease the absorption of oral Doxycycline. Manufacturer ... |
| Calcium lactate | MODERATE | oral Calcium lactate is predicted to decrease the absorption of oral Doxycycline. Manufacturer ad... |
| Calcium phosphate | MODERATE | oral Calcium phosphate is predicted to decrease the absorption of oral Doxycycline. Manufacturer ... |
| Carbamazepine | MODERATE | Carbamazepine decreases the concentration of Doxycycline. Manufacturer advises adjust dose. |
| Enzalutamide | MODERATE | Enzalutamide is predicted to affect the exposure to Doxycycline. Manufacturer advises use with ca... |
| Fosphenytoin | MODERATE | Fosphenytoin is predicted to decrease the concentration of Doxycycline. Manufacturer advises adju... |
| Iron | MODERATE | oral Iron decreases the absorption of oral Doxycycline. Manufacturer advises Doxycycline should b... |
| Kaolin | MODERATE | oral Kaolin is predicted to decrease the absorption of oral Doxycycline. Manufacturer makes no re... |
| Lanthanum | MODERATE | oral Lanthanum might decrease the absorption of oral Doxycycline. Manufacturer advises separate a... |
| Phenobarbital | MODERATE | Phenobarbital decreases the concentration of Doxycycline. Manufacturer advises adjust dose. |
| Phenytoin | MODERATE | Phenytoin decreases the concentration of Doxycycline. Manufacturer advises adjust dose. |
| Primidone | MODERATE | Primidone decreases the concentration of Doxycycline. Manufacturer advises adjust dose. |
| Quinapril | MODERATE | oral Quinapril (magnesium carbonate-containing forms) might decrease the absorption of oral Doxyc... |
| Rifampicin | MODERATE | Rifampicin modestly decreases the exposure to Doxycycline. Manufacturer advises adjust dose. |
| Strontium | MODERATE | Strontium is predicted to decrease the absorption of Doxycycline. Manufacturer advises avoid. |
| Sucralfate | MODERATE | oral Sucralfate might decrease the absorption of oral Doxycycline. Manufacturer advises separatin... |
| Zinc | MODERATE | oral Zinc is predicted to decrease the absorption of Doxycycline. Manufacturer advises separate a... |
| Alectinib | LOW | Both Doxycycline and Alectinib can increase the risk of hepatotoxicity. |
| Amiodarone | LOW | Both Doxycycline and Amiodarone can increase the risk of hepatotoxicity. |
| Anidulafungin | LOW | Both Doxycycline and Anidulafungin can increase the risk of hepatotoxicity. |
| Asparaginase | LOW | Both Doxycycline and Asparaginase can increase the risk of hepatotoxicity. |
| Atorvastatin | LOW | Both Doxycycline and Atorvastatin can increase the risk of hepatotoxicity. |
| Bexarotene | LOW | Both Doxycycline and Bexarotene can increase the risk of hepatotoxicity. |
| Capecitabine | LOW | Both Doxycycline and Capecitabine can increase the risk of hepatotoxicity. |
| Carmustine | LOW | Both Doxycycline and Carmustine can increase the risk of hepatotoxicity. |
| Caspofungin | LOW | Both Doxycycline and Caspofungin can increase the risk of hepatotoxicity. |
| Clofarabine | LOW | Both Doxycycline and Clofarabine can increase the risk of hepatotoxicity. |
| Crisantaspase | LOW | Both Doxycycline and Crisantaspase can increase the risk of hepatotoxicity. |
| Cytarabine | LOW | Both Doxycycline and Cytarabine can increase the risk of hepatotoxicity. |
| Dactinomycin | LOW | Both Doxycycline and Dactinomycin can increase the risk of hepatotoxicity. |
| Decitabine | LOW | Both Doxycycline and Decitabine can increase the risk of hepatotoxicity. |
| Fluconazole | LOW | Both Doxycycline and Fluconazole can increase the risk of hepatotoxicity. |
| Fludarabine | LOW | Both Doxycycline and Fludarabine can increase the risk of hepatotoxicity. |
| Fluorouracil | LOW | Both Doxycycline and Fluorouracil can increase the risk of hepatotoxicity. |
| Flutamide | LOW | Both Doxycycline and Flutamide can increase the risk of hepatotoxicity. |
| Fluvastatin | LOW | Both Doxycycline and Fluvastatin can increase the risk of hepatotoxicity. |
| Gemcitabine | LOW | Both Doxycycline and Gemcitabine can increase the risk of hepatotoxicity. |
| Heparin | LOW | Both Doxycycline and Heparin can increase the risk of hepatotoxicity. |
| Isoniazid | LOW | Both Doxycycline and Isoniazid can increase the risk of hepatotoxicity. |
| Itraconazole | LOW | Both Doxycycline and Itraconazole can increase the risk of hepatotoxicity. |
| Lenalidomide | LOW | Both Doxycycline and Lenalidomide can increase the risk of hepatotoxicity. |
| Lomitapide | LOW | Both Doxycycline and Lomitapide can increase the risk of hepatotoxicity. |
| Mercaptopurine | LOW | Both Doxycycline and Mercaptopurine can increase the risk of hepatotoxicity. |
| Methotrexate | LOW | Both Doxycycline and Methotrexate can increase the risk of hepatotoxicity. |
| Micafungin | LOW | Both Doxycycline and Micafungin can increase the risk of hepatotoxicity. |
| Nelarabine | LOW | Both Doxycycline and Nelarabine can increase the risk of hepatotoxicity. |
| Neratinib | LOW | Both Doxycycline and Neratinib can increase the risk of hepatotoxicity. |
| Nevirapine | LOW | Both Doxycycline and Nevirapine can increase the risk of hepatotoxicity. |
| Nicotinic acid | LOW | Both Doxycycline and Nicotinic acid can increase the risk of hepatotoxicity. |
| Oxandrolone | LOW | Both Doxycycline and Oxandrolone can increase the risk of hepatotoxicity. |
| Oxymetholone | LOW | Both Doxycycline and Oxymetholone can increase the risk of hepatotoxicity. |
| Paracetamol | LOW | Both Doxycycline and Paracetamol can increase the risk of hepatotoxicity. |
| Pegaspargase | LOW | Both Doxycycline and Pegaspargase can increase the risk of hepatotoxicity. |
| Pemetrexed | LOW | Both Doxycycline and Pemetrexed can increase the risk of hepatotoxicity. |
| Pomalidomide | LOW | Both Doxycycline and Pomalidomide can increase the risk of hepatotoxicity. |
| Pravastatin | LOW | Both Doxycycline and Pravastatin can increase the risk of hepatotoxicity. |
| Pyrazinamide | LOW | Both Doxycycline and Pyrazinamide can increase the risk of hepatotoxicity. |
| Ritonavir | LOW | Both Doxycycline and Ritonavir can increase the risk of hepatotoxicity. |
| Rosuvastatin | LOW | Both Doxycycline and Rosuvastatin can increase the risk of hepatotoxicity. |
| Simvastatin | LOW | Both Doxycycline and Simvastatin can increase the risk of hepatotoxicity. |
| Sotorasib | LOW | Both Doxycycline and Sotorasib can increase the risk of hepatotoxicity. |
| Streptozocin | LOW | Both Doxycycline and Streptozocin can increase the risk of hepatotoxicity. |
| Testosterone | LOW | Both Doxycycline and Testosterone can increase the risk of hepatotoxicity. |
| Thalidomide | LOW | Both Doxycycline and Thalidomide can increase the risk of hepatotoxicity. |
| Tigecycline | LOW | Both Doxycycline and Tigecycline can increase the risk of hepatotoxicity. |
| Tioguanine | LOW | Both Doxycycline and Tioguanine can increase the risk of hepatotoxicity. |
| Trabectedin | LOW | Both Doxycycline and Trabectedin can increase the risk of hepatotoxicity. |
| Valproate | LOW | Both Doxycycline and Valproate can increase the risk of hepatotoxicity. |
| Vitamin A | LOW | Both Doxycycline and Vitamin A can increase the risk of hepatotoxicity. |
| Vorasidenib | LOW | Both Doxycycline and Vorasidenib can increase the risk of hepatotoxicity. |
| Voriconazole | LOW | Both Doxycycline and Voriconazole can increase the risk of hepatotoxicity. |
| Zidovudine | LOW | Both Doxycycline and Zidovudine can increase the risk of hepatotoxicity. |
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