Ibuprofen Drug Interactions

250Total Interactions
113Severe
30Moderate
0Mild
DrugSeveritySummary
Acalabrutinib SEVERE Both Ibuprofen and Acalabrutinib can increase the risk of bleeding.
Acenocoumarol SEVERE Acenocoumarol causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of devel...
Alprostadil SEVERE Both Ibuprofen and Alprostadil can increase the risk of bleeding.
Alteplase SEVERE Alteplase causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developin...
Anagrelide SEVERE Both Ibuprofen and Anagrelide can increase the risk of bleeding.
Apixaban SEVERE Apixaban causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developing...
Argatroban SEVERE Argatroban causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developi...
Asparaginase SEVERE Asparaginase causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of develo...
Aspirin SEVERE Both Ibuprofen and Aspirin can increase the risk of bleeding.
Avapritinib SEVERE Ibuprofen might increase the risk of bleeding when given with Avapritinib. Manufacturer advises m...
Axitinib SEVERE Both Ibuprofen and Axitinib can increase the risk of bleeding.
Beclometasone SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Beclometasone. Manufact...
Bemiparin SEVERE Bemiparin causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developin...
Bendroflumethiazide SEVERE Ibuprofen increases the risk of acute renal failure when given with Bendroflumethiazide. Manufact...
Betamethasone SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Betamethasone. Manufact...
Bevacizumab SEVERE Ibuprofen causes bleeding, as can Bevacizumab ; concurrent use might increase the risk of develop...
Bivalirudin SEVERE Bivalirudin causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of develop...
Bosutinib SEVERE Both Ibuprofen and Bosutinib can increase the risk of bleeding.
Budesonide SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Budesonide. Manufacture...
Cabozantinib SEVERE Ibuprofen causes bleeding, as can Cabozantinib ; concurrent use might increase the risk of develo...
Cangrelor SEVERE Both Ibuprofen and Cangrelor can increase the risk of bleeding.
Caplacizumab SEVERE Ibuprofen causes bleeding, as can Caplacizumab ; concurrent use might increase the risk of develo...
Chlorothiazide SEVERE Ibuprofen increases the risk of acute renal failure when given with Chlorothiazide. Manufacturer ...
Chlortalidone SEVERE Ibuprofen increases the risk of acute renal failure when given with Chlortalidone. Manufacturer m...
Ciclesonide SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Ciclesonide. Manufactur...
Cilostazol SEVERE Both Ibuprofen and Cilostazol can increase the risk of bleeding.
Ciprofloxacin SEVERE Ibuprofen potentially increases the risk of seizures when given with Ciprofloxacin. Manufacturer ...
Citalopram SEVERE Both Ibuprofen and Citalopram can increase the risk of bleeding.
Clopidogrel SEVERE Both Ibuprofen and Clopidogrel can increase the risk of bleeding.
Cobimetinib SEVERE Ibuprofen causes bleeding, as can Cobimetinib ; concurrent use might increase the risk of develop...
Crisantaspase SEVERE Crisantaspase causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of devel...
Dabigatran SEVERE Dabigatran causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developi...
Dalteparin SEVERE Dalteparin causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developi...
Danaparoid SEVERE Danaparoid causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developi...
Dapoxetine SEVERE Both Ibuprofen and Dapoxetine can increase the risk of bleeding.
Dasatinib SEVERE Both Ibuprofen and Dasatinib can increase the risk of bleeding.
Deferasirox SEVERE Ibuprofen is predicted to increase the risk of gastrointestinal bleeding when given with Deferasi...
Deflazacort SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Deflazacort. Manufactur...
Delafloxacin SEVERE Ibuprofen potentially increases the risk of seizures when given with Delafloxacin. Manufacturer a...
Dexamethasone SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Dexamethasone. Manufact...
Dipyridamole SEVERE Both Ibuprofen and Dipyridamole can increase the risk of bleeding.
Donanemab SEVERE Donanemab can increase the risk of bleeding when given with Ibuprofen. Manufacturer makes no reco...
Duloxetine SEVERE Both Ibuprofen and Duloxetine can increase the risk of bleeding.
Edoxaban SEVERE Edoxaban causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developing...
Enoxaparin SEVERE Enoxaparin causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developi...
Epoprostenol SEVERE Both Ibuprofen and Epoprostenol can increase the risk of bleeding.
Eptifibatide SEVERE Eptifibatide causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of develo...
Erlotinib SEVERE Erlotinib is predicted to increase the risk of gastrointestinal perforation when given with Ibupr...
Escitalopram SEVERE Both Ibuprofen and Escitalopram can increase the risk of bleeding.
Fludrocortisone SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Fludrocortisone. Manufa...
Fluoxetine SEVERE Both Ibuprofen and Fluoxetine can increase the risk of bleeding.
Fluticasone SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Fluticasone. Manufactur...
Fluvoxamine SEVERE Both Ibuprofen and Fluvoxamine can increase the risk of bleeding.
Fondaparinux SEVERE Fondaparinux causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of develo...
Heparin SEVERE Heparin causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developing ...
Hydrochlorothiazide SEVERE Ibuprofen increases the risk of acute renal failure when given with Hydrochlorothiazide. Manufact...
Hydrocortisone SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Hydrocortisone. Manufac...
Hydroflumethiazide SEVERE Ibuprofen increases the risk of acute renal failure when given with Hydroflumethiazide. Manufactu...
Ibrutinib SEVERE Both Ibuprofen and Ibrutinib can increase the risk of bleeding.
Icosapent SEVERE Both Ibuprofen and Icosapent can increase the risk of bleeding.
Iloprost SEVERE Both Ibuprofen and Iloprost can increase the risk of bleeding.
Imatinib SEVERE Both Ibuprofen and Imatinib can increase the risk of bleeding.
Indapamide SEVERE Ibuprofen increases the risk of acute renal failure when given with Indapamide. Manufacturer make...
Inotersen SEVERE Ibuprofen causes bleeding, as can Inotersen ; concurrent use might increase the risk of developin...
Lecanemab SEVERE Lecanemab can increase the risk of bleeding when given with Ibuprofen. Manufacturer makes no reco...
Lenvatinib SEVERE Both Ibuprofen and Lenvatinib can increase the risk of bleeding.
Levofloxacin SEVERE Ibuprofen potentially increases the risk of seizures when given with Levofloxacin. Manufacturer a...
Lithium SEVERE Ibuprofen increases the concentration of Lithium. Manufacturer advises monitor and adjust dose.
Methotrexate SEVERE Ibuprofen is predicted to increase the risk of toxicity when given with Methotrexate (particularl...
Methylprednisolone SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Methylprednisolone. Man...
Metolazone SEVERE Ibuprofen increases the risk of acute renal failure when given with Metolazone. Manufacturer make...
Mifamurtide SEVERE Ibuprofen (high-dose) is predicted to decrease the efficacy of Mifamurtide. Manufacturer advises ...
Mometasone SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Mometasone. Manufacture...
Moxifloxacin SEVERE Ibuprofen potentially increases the risk of seizures when given with Moxifloxacin. Manufacturer a...
Nicorandil SEVERE Nicorandil is predicted to increase the risk of gastrointestinal perforation when given with Ibup...
Nicotinic acid SEVERE Nicotinic acid causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of deve...
Nintedanib SEVERE Both Ibuprofen and Nintedanib can increase the risk of bleeding.
Ofloxacin SEVERE Ibuprofen potentially increases the risk of seizures when given with Ofloxacin. Manufacturer advi...
Omega-3-acid ethyl esters SEVERE Both Ibuprofen and Omega-3-acid ethyl esters can increase the risk of bleeding.
Paroxetine SEVERE Both Ibuprofen and Paroxetine can increase the risk of bleeding.
Pazopanib SEVERE Both Ibuprofen and Pazopanib can increase the risk of bleeding.
Pegaspargase SEVERE Pegaspargase causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of develo...
Pemetrexed SEVERE Ibuprofen is predicted to increase the exposure to Pemetrexed. Manufacturer advises use with caut...
Pentosan SEVERE Pentosan causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developing...
Phenindione SEVERE Phenindione causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of develop...
Ponatinib SEVERE Both Ibuprofen and Ponatinib can increase the risk of bleeding.
Prasugrel SEVERE Both Ibuprofen and Prasugrel can increase the risk of bleeding.
Prednisolone SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Prednisolone. Manufactu...
Ranibizumab SEVERE Ibuprofen causes bleeding, as can Ranibizumab ; concurrent use might increase the risk of develop...
Regorafenib SEVERE Both Ibuprofen and Regorafenib can increase the risk of bleeding.
Rivaroxaban SEVERE Rivaroxaban causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of develop...
Ruxolitinib SEVERE Ibuprofen causes bleeding, as can Ruxolitinib ; concurrent use might increase the risk of develop...
Sertraline SEVERE Both Ibuprofen and Sertraline can increase the risk of bleeding.
Sorafenib SEVERE Both Ibuprofen and Sorafenib can increase the risk of bleeding.
Streptokinase SEVERE Streptokinase causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of devel...
Sunitinib SEVERE Both Ibuprofen and Sunitinib can increase the risk of bleeding.
Tenecteplase SEVERE Tenecteplase causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of develo...
Ticagrelor SEVERE Both Ibuprofen and Ticagrelor can increase the risk of bleeding.
Tinzaparin SEVERE Tinzaparin causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developi...
Tirofiban SEVERE Tirofiban causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developin...
Trametinib SEVERE Ibuprofen causes bleeding, as can Trametinib ; concurrent use might increase the risk of developi...
Trastuzumab emtansine SEVERE Ibuprofen causes bleeding, as can Trastuzumab emtansine ; concurrent use might increase the risk ...
Treprostinil SEVERE Both Ibuprofen and Treprostinil can increase the risk of bleeding.
Triamcinolone SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Triamcinolone. Manufact...
Urokinase SEVERE Urokinase causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developin...
Vamorolone SEVERE Ibuprofen increases the risk of gastrointestinal bleeding when given with Vamorolone. Manufacture...
Venlafaxine SEVERE Both Ibuprofen and Venlafaxine can increase the risk of bleeding.
Volanesorsen SEVERE Ibuprofen causes bleeding, as can Volanesorsen ; concurrent use might increase the risk of develo...
Vortioxetine SEVERE Both Ibuprofen and Vortioxetine can increase the risk of bleeding.
Warfarin SEVERE Warfarin causes bleeding, as can Ibuprofen ; concurrent use might increase the risk of developing...
Xipamide SEVERE Ibuprofen increases the risk of acute renal failure when given with Xipamide. Manufacturer makes ...
Zanubrutinib SEVERE Both Ibuprofen and Zanubrutinib can increase the risk of bleeding.
Zidovudine SEVERE Zidovudine increases the risk of haematological toxicity when given with Ibuprofen. Manufacturer ...
Alendronate MODERATE Ibuprofen is predicted to increase the risk of gastrointestinal irritation when given with Alendr...
Amikacin MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Amikacin ; concurrent use might increase th...
Amphotericin B MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Amphotericin B ; concurrent use might incre...
Bumetanide MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Bumetanide ; concurrent use might increase ...
Carboplatin MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Carboplatin ; concurrent use might increase...
Chloroquine MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Chloroquine ; concurrent use might increase...
Cisplatin MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Cisplatin ; concurrent use might increase t...
Clodronate MODERATE Ibuprofen is predicted to increase the risk of renal impairment when given with Clodronate. Manuf...
Colistimethate MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Colistimethate ; concurrent use might incre...
Daptomycin MODERATE Ibuprofen increases the risk of renal impairment when given with Daptomycin. Manufacturer advises...
Furosemide MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Furosemide ; concurrent use might increase ...
Gentamicin MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Gentamicin ; concurrent use might increase ...
Hydroxychloroquine MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Hydroxychloroquine ; concurrent use might i...
Ibandronate MODERATE Ibuprofen is predicted to increase the risk of gastrointestinal irritation when given with Ibandr...
Mefloquine MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Mefloquine ; concurrent use might increase ...
Neomycin MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Neomycin ; concurrent use might increase th...
Netilmicin MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Netilmicin ; concurrent use might increase ...
Oxaliplatin MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Oxaliplatin ; concurrent use might increase...
Quinine MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Quinine ; concurrent use might increase the...
Sparsentan MODERATE Sparsentan is predicted to decrease the exposure to Ibuprofen. Manufacturer advises caution.
Streptomycin MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Streptomycin ; concurrent use might increas...
Teprotumumab MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Teprotumumab ; concurrent use might increas...
Tobramycin MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Tobramycin ; concurrent use might increase ...
Torasemide MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Torasemide ; concurrent use might increase ...
Vancomycin MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Vancomycin ; concurrent use might increase ...
Vinblastine MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Vinblastine ; concurrent use might increase...
Vincristine MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Vincristine ; concurrent use might increase...
Vindesine MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Vindesine ; concurrent use might increase t...
Vinorelbine MODERATE Ibuprofen (high-dose) might cause ototoxicity, as can Vinorelbine ; concurrent use might increase...
Voriconazole MODERATE Voriconazole moderately increases the exposure to Ibuprofen. Manufacturer advises adjust dose.
Aciclovir LOW Both Ibuprofen and Aciclovir can increase the risk of nephrotoxicity.
Aliskiren LOW Both Ibuprofen and Aliskiren can increase the risk of hyperkalaemia (hyperkalaemia is particularl...
Amiloride LOW Both Ibuprofen and Amiloride can increase the risk of hyponatraemia.
Amisulpride LOW Both Ibuprofen and Amisulpride can increase the risk of hyponatraemia.
Amitriptyline LOW Both Ibuprofen and Amitriptyline can increase the risk of hyponatraemia.
Aripiprazole LOW Both Ibuprofen and Aripiprazole can increase the risk of hyponatraemia.
Asenapine LOW Both Ibuprofen and Asenapine can increase the risk of hyponatraemia.
Azilsartan LOW Both Ibuprofen and Azilsartan can increase the risk of hyperkalaemia (hyperkalaemia is particular...
Benperidol LOW Both Ibuprofen and Benperidol can increase the risk of hyponatraemia.
Candesartan LOW Both Ibuprofen and Candesartan can increase the risk of hyperkalaemia (hyperkalaemia is particula...
Captopril LOW Both Ibuprofen and Captopril can increase the risk of nephrotoxicity.
Carbamazepine LOW Both Ibuprofen and Carbamazepine can increase the risk of hyponatraemia.
Cariprazine LOW Both Ibuprofen and Cariprazine can increase the risk of hyponatraemia.
Cefaclor LOW Both Ibuprofen and Cefaclor can increase the risk of nephrotoxicity.
Cefadroxil LOW Both Ibuprofen and Cefadroxil can increase the risk of nephrotoxicity.
Cefalexin LOW Both Ibuprofen and Cefalexin can increase the risk of nephrotoxicity.
Cefazolin LOW Both Ibuprofen and Cefazolin can increase the risk of nephrotoxicity.
Cefepime LOW Both Ibuprofen and Cefepime can increase the risk of nephrotoxicity.
Cefixime LOW Both Ibuprofen and Cefixime can increase the risk of nephrotoxicity.
Cefotaxime LOW Both Ibuprofen and Cefotaxime can increase the risk of nephrotoxicity.
Cefoxitin LOW Both Ibuprofen and Cefoxitin can increase the risk of nephrotoxicity.
Cefradine LOW Both Ibuprofen and Cefradine can increase the risk of nephrotoxicity.
Ceftaroline LOW Both Ibuprofen and Ceftaroline can increase the risk of nephrotoxicity.
Ceftazidime LOW Both Ibuprofen and Ceftazidime can increase the risk of nephrotoxicity.
Ceftobiprole LOW Both Ibuprofen and Ceftobiprole can increase the risk of nephrotoxicity.
Ceftolozane LOW Both Ibuprofen and Ceftolozane can increase the risk of nephrotoxicity.
Ceftriaxone LOW Both Ibuprofen and Ceftriaxone can increase the risk of nephrotoxicity.
Cefuroxime LOW Both Ibuprofen and Cefuroxime can increase the risk of nephrotoxicity.
Chlorpromazine LOW Both Ibuprofen and Chlorpromazine can increase the risk of hyponatraemia.
Ciclosporin LOW Both Ibuprofen and Ciclosporin can increase the risk of nephrotoxicity.
Cidofovir LOW Both Ibuprofen and Cidofovir can increase the risk of nephrotoxicity.
Clomipramine LOW Both Ibuprofen and Clomipramine can increase the risk of hyponatraemia.
Clozapine LOW Both Ibuprofen and Clozapine can increase the risk of hyponatraemia.
Cyclophosphamide LOW Both Ibuprofen and Cyclophosphamide can increase the risk of hyponatraemia.
Desmopressin LOW Both Ibuprofen and Desmopressin can increase the risk of hyponatraemia.
Dosulepin LOW Both Ibuprofen and Dosulepin can increase the risk of hyponatraemia.
Doxepin LOW Both Ibuprofen and Doxepin can increase the risk of hyponatraemia.
Droperidol LOW Both Ibuprofen and Droperidol can increase the risk of hyponatraemia.
Drospirenone LOW Both Ibuprofen and Drospirenone can increase the risk of hyperkalaemia (hyperkalaemia is particul...
Enalapril LOW Both Ibuprofen and Enalapril can increase the risk of nephrotoxicity.
Eplerenone LOW Both Ibuprofen and Eplerenone can increase the risk of hyperkalaemia (hyperkalaemia is particular...
Eprosartan LOW Both Ibuprofen and Eprosartan can increase the risk of hyperkalaemia (hyperkalaemia is particular...
Eslicarbazepine LOW Both Ibuprofen and Eslicarbazepine can increase the risk of hyponatraemia.
Finerenone LOW Both Ibuprofen and Finerenone can increase the risk of hyperkalaemia (hyperkalaemia is particular...
Flupentixol LOW Both Ibuprofen and Flupentixol can increase the risk of hyponatraemia.
Foscarnet LOW Both Ibuprofen and Foscarnet can increase the risk of nephrotoxicity.
Fosinopril LOW Both Ibuprofen and Fosinopril can increase the risk of nephrotoxicity.
Ganciclovir LOW Both Ibuprofen and Ganciclovir can increase the risk of nephrotoxicity.
Haloperidol LOW Both Ibuprofen and Haloperidol can increase the risk of hyponatraemia.
Ifosfamide LOW Both Ibuprofen and Ifosfamide can increase the risk of nephrotoxicity.
Imidapril LOW Both Ibuprofen and Imidapril can increase the risk of nephrotoxicity.
Imipramine LOW Both Ibuprofen and Imipramine can increase the risk of hyponatraemia.
Irbesartan LOW Both Ibuprofen and Irbesartan can increase the risk of hyperkalaemia (hyperkalaemia is particular...
Labetalol LOW Both Ibuprofen and Labetalol can increase the risk of hyperkalaemia (hyperkalaemia is particularl...
Levomepromazine LOW Both Ibuprofen and Levomepromazine can increase the risk of hyponatraemia.
Lisinopril LOW Both Ibuprofen and Lisinopril can increase the risk of nephrotoxicity.
Lofepramine LOW Both Ibuprofen and Lofepramine can increase the risk of hyponatraemia.
Losartan LOW Both Ibuprofen and Losartan can increase the risk of hyperkalaemia (hyperkalaemia is particularly...
Loxapine LOW Both Ibuprofen and Loxapine can increase the risk of hyponatraemia.
Lurasidone LOW Both Ibuprofen and Lurasidone can increase the risk of hyponatraemia.
Mannitol LOW Both Ibuprofen and Mannitol can increase the risk of hyponatraemia.
Mesalazine LOW Both Ibuprofen and Mesalazine can increase the risk of nephrotoxicity.
Mirtazapine LOW Both Ibuprofen and Mirtazapine can increase the risk of hyponatraemia.
Nortriptyline LOW Both Ibuprofen and Nortriptyline can increase the risk of hyponatraemia.
Olanzapine LOW Both Ibuprofen and Olanzapine can increase the risk of hyponatraemia.
Olmesartan LOW Both Ibuprofen and Olmesartan can increase the risk of hyperkalaemia (hyperkalaemia is particular...
Oxcarbazepine LOW Both Ibuprofen and Oxcarbazepine can increase the risk of hyponatraemia.
Oxytocin LOW Both Ibuprofen and Oxytocin can increase the risk of hyponatraemia.
Paliperidone LOW Both Ibuprofen and Paliperidone can increase the risk of hyponatraemia.
Pamidronate LOW Both Ibuprofen and Pamidronate can increase the risk of nephrotoxicity.
Pentamidine LOW Both Ibuprofen and Pentamidine can increase the risk of nephrotoxicity.
Pericyazine LOW Both Ibuprofen and Pericyazine can increase the risk of hyponatraemia.
Perindopril LOW Both Ibuprofen and Perindopril can increase the risk of nephrotoxicity.
Pimozide LOW Both Ibuprofen and Pimozide can increase the risk of hyponatraemia.
Potassium aminobenzoate LOW Both Ibuprofen and Potassium aminobenzoate can increase the risk of hyperkalaemia (hyperkalaemia ...
Potassium canrenoate LOW Both Ibuprofen and Potassium canrenoate can increase the risk of hyperkalaemia (hyperkalaemia is ...
Potassium chloride LOW Both Ibuprofen and Potassium chloride can increase the risk of hyperkalaemia (hyperkalaemia is pa...
Prochlorperazine LOW Both Ibuprofen and Prochlorperazine can increase the risk of hyponatraemia.
Promazine LOW Both Ibuprofen and Promazine can increase the risk of hyponatraemia.
Quetiapine LOW Both Ibuprofen and Quetiapine can increase the risk of hyponatraemia.
Quinapril LOW Both Ibuprofen and Quinapril can increase the risk of nephrotoxicity.
Ramipril LOW Both Ibuprofen and Ramipril can increase the risk of nephrotoxicity.
Rifampicin LOW Both Ibuprofen and Rifampicin can increase the risk of nephrotoxicity.
Risperidone LOW Both Ibuprofen and Risperidone can increase the risk of hyponatraemia.
Spironolactone LOW Both Ibuprofen and Spironolactone can increase the risk of hyperkalaemia (hyperkalaemia is partic...
Streptozocin LOW Both Ibuprofen and Streptozocin can increase the risk of nephrotoxicity.
Sulfasalazine LOW Both Ibuprofen and Sulfasalazine can increase the risk of nephrotoxicity.
Sulpiride LOW Both Ibuprofen and Sulpiride can increase the risk of hyponatraemia.
Suxamethonium LOW Both Ibuprofen and Suxamethonium can increase the risk of hyperkalaemia (hyperkalaemia is particu...
Tacrolimus LOW Both Ibuprofen and Tacrolimus can increase the risk of nephrotoxicity.
Telmisartan LOW Both Ibuprofen and Telmisartan can increase the risk of hyperkalaemia (hyperkalaemia is particula...
Tenofovir disoproxil LOW Both Ibuprofen and Tenofovir disoproxil can increase the risk of nephrotoxicity.
Tolvaptan LOW Both Ibuprofen and Tolvaptan can increase the risk of hyperkalaemia (hyperkalaemia is particularl...
Tramadol LOW Both Ibuprofen and Tramadol can increase the risk of hyponatraemia.
Trandolapril LOW Both Ibuprofen and Trandolapril can increase the risk of nephrotoxicity.
Trazodone LOW Both Ibuprofen and Trazodone can increase the risk of hyponatraemia.
Triamterene LOW Both Ibuprofen and Triamterene can increase the risk of hyperkalaemia (hyperkalaemia is particula...
Trifluoperazine LOW Both Ibuprofen and Trifluoperazine can increase the risk of hyponatraemia.
Trimethoprim LOW Both Ibuprofen and Trimethoprim can increase the risk of nephrotoxicity.
Trimipramine LOW Both Ibuprofen and Trimipramine can increase the risk of hyponatraemia.
Valaciclovir LOW Both Ibuprofen and Valaciclovir can increase the risk of nephrotoxicity.
Valganciclovir LOW Both Ibuprofen and Valganciclovir can increase the risk of nephrotoxicity.
Valproate LOW Both Ibuprofen and Valproate can increase the risk of hyponatraemia.
Valsartan LOW Both Ibuprofen and Valsartan can increase the risk of hyperkalaemia (hyperkalaemia is particularl...
Voclosporin LOW Both Ibuprofen and Voclosporin can increase the risk of nephrotoxicity.
Zoledronate LOW Both Ibuprofen and Zoledronate can increase the risk of nephrotoxicity.
Zuclopenthixol LOW Both Ibuprofen and Zuclopenthixol can increase the risk of hyponatraemia.

Check Ibuprofen against your patient's full medication list

InteractRx checks all drug combinations at once — built for GP surgery pharmacists.

Use the Free Checker