Pioglitazone Drug Interactions
41Total Interactions
2Severe
13Moderate
1Mild
| Drug | Severity | Summary |
|---|---|---|
| Clopidogrel | SEVERE | Clopidogrel increases the exposure to Pioglitazone. Manufacturer advises monitor blood glucose an... |
| Gemfibrozil | SEVERE | Gemfibrozil increases the exposure to Pioglitazone. Manufacturer advises monitor blood glucose an... |
| Abiraterone | MODERATE | Abiraterone slightly increases the exposure to Pioglitazone. Manufacturer advises monitor blood g... |
| Clarithromycin | MODERATE | Clarithromycin might cause hypoglycaemia when given with Pioglitazone. Manufacturer advises monit... |
| Deferasirox | MODERATE | Deferasirox is predicted to increase the exposure to Pioglitazone. Manufacturer advises monitor. |
| Fenfluramine | MODERATE | Fenfluramine might decrease blood glucose concentrations when given with Pioglitazone. Manufactur... |
| Isavuconazole | MODERATE | Pioglitazone potentially decreases the exposure to Isavuconazole. Manufacturer advises use with c... |
| Leflunomide | MODERATE | Leflunomide is predicted to increase the exposure to Pioglitazone. Manufacturer advises monitor. |
| Mifepristone | MODERATE | Mifepristone is predicted to increase the exposure to Pioglitazone. Manufacturer makes no recomme... |
| Opicapone | MODERATE | Opicapone is predicted to increase the exposure to Pioglitazone. Manufacturer advises avoid. |
| Pirtobrutinib | MODERATE | Pirtobrutinib is predicted to increase the exposure to Pioglitazone. Manufacturer advises caution. |
| Rifampicin | MODERATE | Rifampicin moderately decreases the exposure to Pioglitazone. Manufacturer advises monitor and ad... |
| Somapacitan | MODERATE | Somapacitan might increase blood glucose concentrations, opposing the blood glucose-lowering effe... |
| Somatrogon | MODERATE | Somatrogon might increase blood glucose concentrations, opposing the blood glucose-lowering effec... |
| Teriflunomide | MODERATE | Teriflunomide is predicted to increase the exposure to Pioglitazone. Manufacturer advises monitor. |
| St John's wort | MILD | St John's wort slightly decreases the exposure to Pioglitazone. Manufacturer makes no recommendat... |
| Acarbose | LOW | Both Pioglitazone and Acarbose can increase the risk of hypoglycaemia. |
| Alogliptin | LOW | Both Pioglitazone and Alogliptin can increase the risk of hypoglycaemia. |
| Canagliflozin | LOW | Both Pioglitazone and Canagliflozin can increase the risk of hypoglycaemia. |
| Dapagliflozin | LOW | Both Pioglitazone and Dapagliflozin can increase the risk of hypoglycaemia. |
| Dulaglutide | LOW | Both Pioglitazone and Dulaglutide can increase the risk of hypoglycaemia. |
| Empagliflozin | LOW | Both Pioglitazone and Empagliflozin can increase the risk of hypoglycaemia. |
| Ertugliflozin | LOW | Both Pioglitazone and Ertugliflozin can increase the risk of hypoglycaemia. |
| Exenatide | LOW | Both Pioglitazone and Exenatide can increase the risk of hypoglycaemia. |
| Glibenclamide | LOW | Both Pioglitazone and Glibenclamide can increase the risk of hypoglycaemia. |
| Gliclazide | LOW | Both Pioglitazone and Gliclazide can increase the risk of hypoglycaemia. |
| Glimepiride | LOW | Both Pioglitazone and Glimepiride can increase the risk of hypoglycaemia. |
| Glipizide | LOW | Both Pioglitazone and Glipizide can increase the risk of hypoglycaemia. |
| Insulin | LOW | Both Pioglitazone and Insulin can increase the risk of hypoglycaemia. |
| Linagliptin | LOW | Both Pioglitazone and Linagliptin can increase the risk of hypoglycaemia. |
| Liraglutide | LOW | Both Pioglitazone and Liraglutide can increase the risk of hypoglycaemia. |
| Lixisenatide | LOW | Both Pioglitazone and Lixisenatide can increase the risk of hypoglycaemia. |
| Metformin | LOW | Both Pioglitazone and Metformin can increase the risk of hypoglycaemia. |
| Repaglinide | LOW | Both Pioglitazone and Repaglinide can increase the risk of hypoglycaemia. |
| Saxagliptin | LOW | Both Pioglitazone and Saxagliptin can increase the risk of hypoglycaemia. |
| Semaglutide | LOW | Both Pioglitazone and Semaglutide can increase the risk of hypoglycaemia. |
| Sitagliptin | LOW | Both Pioglitazone and Sitagliptin can increase the risk of hypoglycaemia. |
| Tirzepatide | LOW | Both Pioglitazone and Tirzepatide can increase the risk of hypoglycaemia. |
| Tolbutamide | LOW | Both Pioglitazone and Tolbutamide can increase the risk of hypoglycaemia. |
| Vildagliptin | LOW | Both Pioglitazone and Vildagliptin can increase the risk of hypoglycaemia. |
| Ivosidenib | UNKNOWN | Ivosidenib might decrease the exposure to Pioglitazone. Manufacturer advises avoid or monitor eff... |
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