Tramadol Drug Interactions
219Total Interactions
22Severe
2Moderate
0Mild
| Drug | Severity | Summary |
|---|---|---|
| Acenocoumarol | SEVERE | Tramadol might increase the anticoagulant effect of Acenocoumarol. Manufacturer advises caution. |
| Buprenorphine | SEVERE | Buprenorphine is predicted to increase the risk of opiate withdrawal when given with Tramadol. Ma... |
| Bupropion | SEVERE | Bupropion is predicted to decrease the efficacy of Tramadol. Manufacturer makes no recommendation. |
| Carbamazepine | SEVERE | Carbamazepine decreases the concentration of Tramadol. Manufacturer advises adjust dose. |
| Cinacalcet | SEVERE | Cinacalcet is predicted to decrease the efficacy of Tramadol. Manufacturer makes no recommendation. |
| Clozapine | SEVERE | Clozapine can cause constipation, as can Tramadol ; concurrent use might increase the risk of dev... |
| Dacomitinib | SEVERE | Dacomitinib is predicted to decrease the efficacy of Tramadol. Manufacturer makes no recommendation. |
| Fluoxetine | SEVERE | Fluoxetine is predicted to decrease the efficacy of Tramadol. Manufacturer makes no recommendation. |
| Isocarboxazid | SEVERE | Tramadol is predicted to increase the risk of CNS excitation or depression when given with Isocar... |
| Meptazinol | SEVERE | Meptazinol is predicted to increase the risk of opiate withdrawal when given with Tramadol. Manuf... |
| Moclobemide | SEVERE | Moclobemide might cause serotonin syndrome, as can Tramadol ; concurrent use might increase the r... |
| Nalmefene | SEVERE | Nalmefene is predicted to decrease the efficacy of Tramadol. Manufacturer advises avoid except in... |
| Naltrexone | SEVERE | Naltrexone is predicted to decrease the efficacy of Tramadol. Manufacturer advises avoid except i... |
| Ozanimod | SEVERE | Tramadol might increase the risk of adverse effects when given with Ozanimod. Manufacturer makes ... |
| Paroxetine | SEVERE | Paroxetine is predicted to decrease the efficacy of Tramadol. Manufacturer makes no recommendation. |
| Pentazocine | SEVERE | Pentazocine is predicted to increase the risk of opiate withdrawal when given with Tramadol. Manu... |
| Phenelzine | SEVERE | Tramadol is predicted to increase the risk of CNS excitation or depression when given with Phenel... |
| Phenindione | SEVERE | Tramadol might increase the anticoagulant effect of Phenindione. Manufacturer advises caution. |
| Tapentadol | SEVERE | Tapentadol is predicted to increase the risk of serotonin syndrome when given with Tramadol. Manu... |
| Terbinafine | SEVERE | Terbinafine is predicted to decrease the efficacy of Tramadol. Manufacturer makes no recommendation. |
| Tranylcypromine | SEVERE | Tramadol is predicted to increase the risk of CNS excitation or depression when given with Tranyl... |
| Warfarin | SEVERE | Tramadol has been reported to increase the anticoagulant effect of Warfarin. Manufacturer advises... |
| Enzalutamide | MODERATE | Enzalutamide is predicted to affect the exposure to Tramadol. Manufacturer advises use with cauti... |
| Mexiletine | MODERATE | Tramadol potentially decreases the absorption of oral Mexiletine. Manufacturer makes no recommend... |
| Aceclofenac | LOW | Both Tramadol and Aceclofenac can increase the risk of hyponatraemia. |
| Agomelatine | LOW | Both Tramadol and Agomelatine have effects on the CNS and can cause sedation, which might affect ... |
| Alcohol | LOW | Both Tramadol and Alcohol have effects on the CNS and can cause sedation, which might affect the ... |
| Alimemazine | LOW | Both Tramadol and Alimemazine have effects on the CNS and can cause sedation, which might affect ... |
| Almotriptan | LOW | Both Tramadol and Almotriptan can increase the risk of serotonin syndrome. See 'Serotonin syndrom... |
| Alprazolam | LOW | Both Tramadol and Alprazolam have effects on the CNS and can cause sedation, which might affect t... |
| Amiloride | LOW | Both Tramadol and Amiloride can increase the risk of hyponatraemia. |
| Amisulpride | LOW | Both Tramadol and Amisulpride can increase the risk of hyponatraemia. |
| Amitriptyline | LOW | Both Tramadol and Amitriptyline can increase the risk of hyponatraemia. |
| Apomorphine | LOW | Both Tramadol and Apomorphine have effects on the CNS and can cause sedation, which might affect ... |
| Apraclonidine | LOW | Both Tramadol and Apraclonidine have effects on the CNS and can cause sedation, which might affec... |
| Aripiprazole | LOW | Both Tramadol and Aripiprazole can increase the risk of hyponatraemia. |
| Asenapine | LOW | Both Tramadol and Asenapine can increase the risk of hyponatraemia. |
| Baclofen | LOW | Both Tramadol and Baclofen have effects on the CNS and can cause sedation, which might affect the... |
| Bendroflumethiazide | LOW | Both Tramadol and Bendroflumethiazide can increase the risk of hyponatraemia. |
| Benperidol | LOW | Both Tramadol and Benperidol can increase the risk of hyponatraemia. |
| Brimonidine | LOW | Both Tramadol and Brimonidine have effects on the CNS and can cause sedation, which might affect ... |
| Bromocriptine | LOW | Both Tramadol and Bromocriptine have effects on the CNS and can cause sedation, which might affec... |
| Buclizine | LOW | Both Tramadol and Buclizine have effects on the CNS and can cause sedation, which might affect th... |
| Bumetanide | LOW | Both Tramadol and Bumetanide can increase the risk of hyponatraemia. |
| Cabergoline | LOW | Both Tramadol and Cabergoline have effects on the CNS and can cause sedation, which might affect ... |
| Cannabidiol | LOW | Both Tramadol and Cannabidiol have effects on the CNS and can cause sedation, which might affect ... |
| Carboplatin | LOW | Both Tramadol and Carboplatin can increase the risk of hyponatraemia. |
| Cariprazine | LOW | Both Tramadol and Cariprazine can increase the risk of hyponatraemia. |
| Celecoxib | LOW | Both Tramadol and Celecoxib can increase the risk of hyponatraemia. |
| Cenobamate | LOW | Both Tramadol and Cenobamate have effects on the CNS and can cause sedation, which might affect t... |
| Chloral hydrate | LOW | Both Tramadol and Chloral hydrate have effects on the CNS and can cause sedation, which might aff... |
| Chlordiazepoxide | LOW | Both Tramadol and Chlordiazepoxide have effects on the CNS and can cause sedation, which might af... |
| Chlorothiazide | LOW | Both Tramadol and Chlorothiazide can increase the risk of hyponatraemia. |
| Chlorphenamine | LOW | Both Tramadol and Chlorphenamine have effects on the CNS and can cause sedation, which might affe... |
| Chlorpromazine | LOW | Both Tramadol and Chlorpromazine can increase the risk of hyponatraemia. |
| Chlortalidone | LOW | Both Tramadol and Chlortalidone can increase the risk of hyponatraemia. |
| Cinnarizine | LOW | Both Tramadol and Cinnarizine have effects on the CNS and can cause sedation, which might affect ... |
| Cisplatin | LOW | Both Tramadol and Cisplatin can increase the risk of hyponatraemia. |
| Citalopram | LOW | Both Tramadol and Citalopram can increase the risk of hyponatraemia. |
| Clobazam | LOW | Both Tramadol and Clobazam have effects on the CNS and can cause sedation, which might affect the... |
| Clomethiazole | LOW | Both Tramadol and Clomethiazole have effects on the CNS and can cause sedation, which might affec... |
| Clomipramine | LOW | Both Tramadol and Clomipramine can increase the risk of hyponatraemia. |
| Clonazepam | LOW | Both Tramadol and Clonazepam have effects on the CNS and can cause sedation, which might affect t... |
| Clonidine | LOW | Both Tramadol and Clonidine have effects on the CNS and can cause sedation, which might affect th... |
| Cyclizine | LOW | Both Tramadol and Cyclizine have effects on the CNS and can cause sedation, which might affect th... |
| Cyclophosphamide | LOW | Both Tramadol and Cyclophosphamide can increase the risk of hyponatraemia. |
| Cyproheptadine | LOW | Both Tramadol and Cyproheptadine have effects on the CNS and can cause sedation, which might affe... |
| Dapoxetine | LOW | Both Tramadol and Dapoxetine can increase the risk of serotonin syndrome. See 'Serotonin syndrome... |
| Daridorexant | LOW | Both Tramadol and Daridorexant have effects on the CNS and can cause sedation, which might affect... |
| Desflurane | LOW | Both Tramadol and Desflurane have effects on the CNS and can cause sedation, which might affect t... |
| Desmopressin | LOW | Both Tramadol and Desmopressin can increase the risk of hyponatraemia. |
| Dexamfetamine | LOW | Both Tramadol and Dexamfetamine can increase the risk of serotonin syndrome. See 'Serotonin syndr... |
| Dexketoprofen | LOW | Both Tramadol and Dexketoprofen can increase the risk of hyponatraemia. |
| Dexmedetomidine | LOW | Both Tramadol and Dexmedetomidine have effects on the CNS and can cause sedation, which might aff... |
| Diazepam | LOW | Both Tramadol and Diazepam have effects on the CNS and can cause sedation, which might affect the... |
| Diclofenac | LOW | Both Tramadol and Diclofenac can increase the risk of hyponatraemia. |
| Difelikefalin | LOW | Both Tramadol and Difelikefalin have effects on the CNS and can cause sedation, which might affec... |
| Dimenhydrinate | LOW | Both Tramadol and Dimenhydrinate have effects on the CNS and can cause sedation, which might affe... |
| Dosulepin | LOW | Both Tramadol and Dosulepin can increase the risk of hyponatraemia. |
| Doxepin | LOW | Both Tramadol and Doxepin can increase the risk of hyponatraemia. |
| Doxylamine | LOW | Both Tramadol and Doxylamine have effects on the CNS and can cause sedation, which might affect t... |
| Dronabinol | LOW | Both Tramadol and Dronabinol have effects on the CNS and can cause sedation, which might affect t... |
| Droperidol | LOW | Both Tramadol and Droperidol can increase the risk of hyponatraemia. |
| Duloxetine | LOW | Both Tramadol and Duloxetine can increase the risk of hyponatraemia. |
| Eletriptan | LOW | Both Tramadol and Eletriptan can increase the risk of serotonin syndrome. See 'Serotonin syndrome... |
| Escitalopram | LOW | Both Tramadol and Escitalopram can increase the risk of hyponatraemia. |
| Esketamine | LOW | Both Tramadol and Esketamine have effects on the CNS and can cause sedation, which might affect t... |
| Eslicarbazepine | LOW | Both Tramadol and Eslicarbazepine can increase the risk of hyponatraemia. |
| Eszopiclone | LOW | Both Tramadol and Eszopiclone have effects on the CNS and can cause sedation, which might affect ... |
| Etodolac | LOW | Both Tramadol and Etodolac can increase the risk of hyponatraemia. |
| Etomidate | LOW | Both Tramadol and Etomidate have effects on the CNS and can cause sedation, which might affect th... |
| Etoricoxib | LOW | Both Tramadol and Etoricoxib can increase the risk of hyponatraemia. |
| Fenfluramine | LOW | Both Tramadol and Fenfluramine can increase the risk of serotonin syndrome. See 'Serotonin syndro... |
| Flupentixol | LOW | Both Tramadol and Flupentixol can increase the risk of hyponatraemia. |
| Flurazepam | LOW | Both Tramadol and Flurazepam have effects on the CNS and can cause sedation, which might affect t... |
| Flurbiprofen | LOW | Both Tramadol and Flurbiprofen can increase the risk of hyponatraemia. |
| Fluvoxamine | LOW | Both Tramadol and Fluvoxamine can increase the risk of hyponatraemia. |
| Foslevodopa | LOW | Both Tramadol and Foslevodopa have effects on the CNS and can cause sedation, which might affect ... |
| Fosphenytoin | LOW | Both Tramadol and Fosphenytoin have effects on the CNS and can cause sedation, which might affect... |
| Frovatriptan | LOW | Both Tramadol and Frovatriptan can increase the risk of serotonin syndrome. See 'Serotonin syndro... |
| Furosemide | LOW | Both Tramadol and Furosemide can increase the risk of hyponatraemia. |
| Gabapentin | LOW | Both Tramadol and Gabapentin have effects on the CNS and can cause sedation, which might affect t... |
| Granisetron | LOW | Both Tramadol and Granisetron can increase the risk of serotonin syndrome. See 'Serotonin syndrom... |
| Guanfacine | LOW | Both Tramadol and Guanfacine have effects on the CNS and can cause sedation, which might affect t... |
| Haloperidol | LOW | Both Tramadol and Haloperidol can increase the risk of hyponatraemia. |
| Hydrochlorothiazide | LOW | Both Tramadol and Hydrochlorothiazide can increase the risk of hyponatraemia. |
| Hydroflumethiazide | LOW | Both Tramadol and Hydroflumethiazide can increase the risk of hyponatraemia. |
| Hydroxyzine | LOW | Both Tramadol and Hydroxyzine have effects on the CNS and can cause sedation, which might affect ... |
| Ibuprofen | LOW | Both Tramadol and Ibuprofen can increase the risk of hyponatraemia. |
| Imipramine | LOW | Both Tramadol and Imipramine can increase the risk of hyponatraemia. |
| Indapamide | LOW | Both Tramadol and Indapamide can increase the risk of hyponatraemia. |
| Indometacin | LOW | Both Tramadol and Indometacin can increase the risk of hyponatraemia. |
| Isoflurane | LOW | Both Tramadol and Isoflurane have effects on the CNS and can cause sedation, which might affect t... |
| Ketamine | LOW | Both Tramadol and Ketamine have effects on the CNS and can cause sedation, which might affect the... |
| Ketoprofen | LOW | Both Tramadol and Ketoprofen can increase the risk of hyponatraemia. |
| Ketorolac | LOW | Both Tramadol and Ketorolac can increase the risk of hyponatraemia. |
| Ketotifen | LOW | Both Tramadol and Ketotifen have effects on the CNS and can cause sedation, which might affect th... |
| Lamotrigine | LOW | Both Tramadol and Lamotrigine have effects on the CNS and can cause sedation, which might affect ... |
| Levetiracetam | LOW | Both Tramadol and Levetiracetam have effects on the CNS and can cause sedation, which might affec... |
| Levodopa | LOW | Both Tramadol and Levodopa have effects on the CNS and can cause sedation, which might affect the... |
| Levomepromazine | LOW | Both Tramadol and Levomepromazine can increase the risk of hyponatraemia. |
| Linezolid | LOW | Both Tramadol and Linezolid can increase the risk of serotonin syndrome. See 'Serotonin syndrome'... |
| Lisdexamfetamine | LOW | Both Tramadol and Lisdexamfetamine can increase the risk of serotonin syndrome. See 'Serotonin sy... |
| Lithium | LOW | Both Tramadol and Lithium can increase the risk of serotonin syndrome. See 'Serotonin syndrome' a... |
| Lofepramine | LOW | Both Tramadol and Lofepramine can increase the risk of hyponatraemia. |
| Lofexidine | LOW | Both Tramadol and Lofexidine have effects on the CNS and can cause sedation, which might affect t... |
| Loprazolam | LOW | Both Tramadol and Loprazolam have effects on the CNS and can cause sedation, which might affect t... |
| Lorazepam | LOW | Both Tramadol and Lorazepam have effects on the CNS and can cause sedation, which might affect th... |
| Lormetazepam | LOW | Both Tramadol and Lormetazepam have effects on the CNS and can cause sedation, which might affect... |
| Loxapine | LOW | Both Tramadol and Loxapine can increase the risk of hyponatraemia. |
| Lurasidone | LOW | Both Tramadol and Lurasidone can increase the risk of hyponatraemia. |
| Mannitol | LOW | Both Tramadol and Mannitol can increase the risk of hyponatraemia. |
| Mefenamic acid | LOW | Both Tramadol and Mefenamic acid can increase the risk of hyponatraemia. |
| Melatonin | LOW | Both Tramadol and Melatonin have effects on the CNS and can cause sedation, which might affect th... |
| Meloxicam | LOW | Both Tramadol and Meloxicam can increase the risk of hyponatraemia. |
| Methocarbamol | LOW | Both Tramadol and Methocarbamol have effects on the CNS and can cause sedation, which might affec... |
| Methoxyflurane | LOW | Both Tramadol and Methoxyflurane have effects on the CNS and can cause sedation, which might affe... |
| Methylthioninium chloride | LOW | Both Tramadol and Methylthioninium chloride can increase the risk of serotonin syndrome. See 'Ser... |
| Metolazone | LOW | Both Tramadol and Metolazone can increase the risk of hyponatraemia. |
| Mianserin | LOW | Both Tramadol and Mianserin have effects on the CNS and can cause sedation, which might affect th... |
| Midazolam | LOW | Both Tramadol and Midazolam have effects on the CNS and can cause sedation, which might affect th... |
| Mirtazapine | LOW | Both Tramadol and Mirtazapine can increase the risk of hyponatraemia. |
| Moxonidine | LOW | Both Tramadol and Moxonidine have effects on the CNS and can cause sedation, which might affect t... |
| Nabilone | LOW | Both Tramadol and Nabilone have effects on the CNS and can cause sedation, which might affect the... |
| Nabumetone | LOW | Both Tramadol and Nabumetone can increase the risk of hyponatraemia. |
| Naproxen | LOW | Both Tramadol and Naproxen can increase the risk of hyponatraemia. |
| Naratriptan | LOW | Both Tramadol and Naratriptan can increase the risk of serotonin syndrome. See 'Serotonin syndrom... |
| Nitrazepam | LOW | Both Tramadol and Nitrazepam have effects on the CNS and can cause sedation, which might affect t... |
| Nitrous oxide | LOW | Both Tramadol and Nitrous oxide have effects on the CNS and can cause sedation, which might affec... |
| Nortriptyline | LOW | Both Tramadol and Nortriptyline can increase the risk of hyponatraemia. |
| Olanzapine | LOW | Both Tramadol and Olanzapine can increase the risk of hyponatraemia. |
| Ondansetron | LOW | Both Tramadol and Ondansetron can increase the risk of serotonin syndrome. See 'Serotonin syndrom... |
| Orphenadrine | LOW | Both Tramadol and Orphenadrine have effects on the CNS and can cause sedation, which might affect... |
| Oxazepam | LOW | Both Tramadol and Oxazepam have effects on the CNS and can cause sedation, which might affect the... |
| Oxcarbazepine | LOW | Both Tramadol and Oxcarbazepine can increase the risk of hyponatraemia. |
| Oxytocin | LOW | Both Tramadol and Oxytocin can increase the risk of hyponatraemia. |
| Paliperidone | LOW | Both Tramadol and Paliperidone can increase the risk of hyponatraemia. |
| Palonosetron | LOW | Both Tramadol and Palonosetron can increase the risk of serotonin syndrome. See 'Serotonin syndro... |
| Parecoxib | LOW | Both Tramadol and Parecoxib can increase the risk of hyponatraemia. |
| Perampanel | LOW | Both Tramadol and Perampanel have effects on the CNS and can cause sedation, which might affect t... |
| Pericyazine | LOW | Both Tramadol and Pericyazine can increase the risk of hyponatraemia. |
| Phenazone | LOW | Both Tramadol and Phenazone can increase the risk of hyponatraemia. |
| Phenobarbital | LOW | Both Tramadol and Phenobarbital have effects on the CNS and can cause sedation, which might affec... |
| Phenytoin | LOW | Both Tramadol and Phenytoin have effects on the CNS and can cause sedation, which might affect th... |
| Pimozide | LOW | Both Tramadol and Pimozide can increase the risk of hyponatraemia. |
| Piroxicam | LOW | Both Tramadol and Piroxicam can increase the risk of hyponatraemia. |
| Pizotifen | LOW | Both Tramadol and Pizotifen have effects on the CNS and can cause sedation, which might affect th... |
| Pramipexole | LOW | Both Tramadol and Pramipexole have effects on the CNS and can cause sedation, which might affect ... |
| Pregabalin | LOW | Both Tramadol and Pregabalin have effects on the CNS and can cause sedation, which might affect t... |
| Primidone | LOW | Both Tramadol and Primidone have effects on the CNS and can cause sedation, which might affect th... |
| Prochlorperazine | LOW | Both Tramadol and Prochlorperazine can increase the risk of hyponatraemia. |
| Procyclidine | LOW | Both Tramadol and Procyclidine have effects on the CNS and can cause sedation, which might affect... |
| Promazine | LOW | Both Tramadol and Promazine can increase the risk of hyponatraemia. |
| Promethazine | LOW | Both Tramadol and Promethazine have effects on the CNS and can cause sedation, which might affect... |
| Propofol | LOW | Both Tramadol and Propofol have effects on the CNS and can cause sedation, which might affect the... |
| Quetiapine | LOW | Both Tramadol and Quetiapine can increase the risk of hyponatraemia. |
| Quinagolide | LOW | Both Tramadol and Quinagolide have effects on the CNS and can cause sedation, which might affect ... |
| Rasagiline | LOW | Both Tramadol and Rasagiline can increase the risk of serotonin syndrome. See 'Serotonin syndrome... |
| Remimazolam | LOW | Both Tramadol and Remimazolam have effects on the CNS and can cause sedation, which might affect ... |
| Risperidone | LOW | Both Tramadol and Risperidone can increase the risk of hyponatraemia. |
| Rizatriptan | LOW | Both Tramadol and Rizatriptan can increase the risk of serotonin syndrome. See 'Serotonin syndrom... |
| Ropinirole | LOW | Both Tramadol and Ropinirole have effects on the CNS and can cause sedation, which might affect t... |
| Rotigotine | LOW | Both Tramadol and Rotigotine have effects on the CNS and can cause sedation, which might affect t... |
| Rufinamide | LOW | Both Tramadol and Rufinamide have effects on the CNS and can cause sedation, which might affect t... |
| Safinamide | LOW | Both Tramadol and Safinamide can increase the risk of serotonin syndrome. See 'Serotonin syndrome... |
| Selegiline | LOW | Both Tramadol and Selegiline can increase the risk of serotonin syndrome. See 'Serotonin syndrome... |
| Sertraline | LOW | Both Tramadol and Sertraline can increase the risk of hyponatraemia. |
| Sevoflurane | LOW | Both Tramadol and Sevoflurane have effects on the CNS and can cause sedation, which might affect ... |
| Sodium oxybate | LOW | Both Tramadol and Sodium oxybate have effects on the CNS and can cause sedation, which might affe... |
| St John's wort | LOW | Both Tramadol and St John's wort can increase the risk of serotonin syndrome. See 'Serotonin synd... |
| Sulindac | LOW | Both Tramadol and Sulindac can increase the risk of hyponatraemia. |
| Sulpiride | LOW | Both Tramadol and Sulpiride can increase the risk of hyponatraemia. |
| Sumatriptan | LOW | Both Tramadol and Sumatriptan can increase the risk of serotonin syndrome. See 'Serotonin syndrom... |
| Temazepam | LOW | Both Tramadol and Temazepam have effects on the CNS and can cause sedation, which might affect th... |
| Tenoxicam | LOW | Both Tramadol and Tenoxicam can increase the risk of hyponatraemia. |
| Tetrabenazine | LOW | Both Tramadol and Tetrabenazine have effects on the CNS and can cause sedation, which might affec... |
| Thalidomide | LOW | Both Tramadol and Thalidomide have effects on the CNS and can cause sedation, which might affect ... |
| Thiopental | LOW | Both Tramadol and Thiopental have effects on the CNS and can cause sedation, which might affect t... |
| Tiaprofenic acid | LOW | Both Tramadol and Tiaprofenic acid can increase the risk of hyponatraemia. |
| Tizanidine | LOW | Both Tramadol and Tizanidine have effects on the CNS and can cause sedation, which might affect t... |
| Tolfenamic acid | LOW | Both Tramadol and Tolfenamic acid can increase the risk of hyponatraemia. |
| Torasemide | LOW | Both Tramadol and Torasemide can increase the risk of hyponatraemia. |
| Trazodone | LOW | Both Tramadol and Trazodone can increase the risk of hyponatraemia. |
| Trifluoperazine | LOW | Both Tramadol and Trifluoperazine can increase the risk of hyponatraemia. |
| Trihexyphenidyl | LOW | Both Tramadol and Trihexyphenidyl have effects on the CNS and can cause sedation, which might aff... |
| Trimipramine | LOW | Both Tramadol and Trimipramine can increase the risk of hyponatraemia. |
| Tryptophan | LOW | Both Tramadol and Tryptophan can increase the risk of serotonin syndrome. See 'Serotonin syndrome... |
| Valproate | LOW | Both Tramadol and Valproate can increase the risk of hyponatraemia. |
| Venlafaxine | LOW | Both Tramadol and Venlafaxine can increase the risk of hyponatraemia. |
| Vigabatrin | LOW | Both Tramadol and Vigabatrin have effects on the CNS and can cause sedation, which might affect t... |
| Vinblastine | LOW | Both Tramadol and Vinblastine can increase the risk of hyponatraemia. |
| Vincristine | LOW | Both Tramadol and Vincristine can increase the risk of hyponatraemia. |
| Vinorelbine | LOW | Both Tramadol and Vinorelbine can increase the risk of hyponatraemia. |
| Vortioxetine | LOW | Both Tramadol and Vortioxetine can increase the risk of serotonin syndrome. See 'Serotonin syndro... |
| Xipamide | LOW | Both Tramadol and Xipamide can increase the risk of hyponatraemia. |
| Zolmitriptan | LOW | Both Tramadol and Zolmitriptan can increase the risk of serotonin syndrome. See 'Serotonin syndro... |
| Zolpidem | LOW | Both Tramadol and Zolpidem have effects on the CNS and can cause sedation, which might affect the... |
| Zopiclone | LOW | Both Tramadol and Zopiclone have effects on the CNS and can cause sedation, which might affect th... |
| Zuclopenthixol | LOW | Both Tramadol and Zuclopenthixol can increase the risk of hyponatraemia. |
Check Tramadol against your patient's full medication list
InteractRx checks all drug combinations at once — built for GP surgery pharmacists.
Use the Free Checker