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SEVERE

Hydroxychloroquine and Osilodrostat Interaction

Both Hydroxychloroquine and Osilodrostat prolong the QT interval. Most manufacturers advise avoiding the use of two or more drugs that are associated with QT prolongation. Increasing age, female sex, cardiac disease, and some metabolic disturbances (notably hypokalaemia) predispose to QT prolongation.

Additive effect
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